Palmitoyl serotonin
Based on 1 Customer Validation
Palmitoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin, antagonist of FAAH. Palmitoyl serotonin inhibits L-3,4-dihydroxyphenylalanine (HY-N0304) induced abnormal involuntary movements. Palmitoyl serotonin has the potential for the research of parkinson's disease (PD).
For research use only. We do not sell to patients.
- Purity: 99.9%
- CAS No.: 212707-51-2
- Formula: C26H42N2O2
- Molecular Weight:414.62
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:25-28 g, Eight-week-old male C57BL/6J mice ( 6-hydroxydopamine (6-OHDA)-induced hemiparkinsonian mouse model)[1]
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Dosage:0.3 mg/kg
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Administration:daily for 10 days
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Result:Reduced axial, limb, and locomotive AIM scores on day 10, suppressed the hyper-phosphorylation of ERK1/2 in the 6-OHDA-lesioned striatum, suppressed the overexpression of FosB and ΔFosB in the 6-OHDA-lesioned striatum.
Chemical Information
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CAS No. 212707-51-2
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Appearance Solid
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Molecular Weight 414.62
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Formula C26H42N2O2
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Color White to off-white
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SMILES
CCCCCCCCCCCCCCCC(NCCC1=CNC2=C1C=C(O)C=C2)=O
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Synonyms
PA-5HT
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMF : 30 mg/mL (72.36 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMF | 1 mM | 2.4118 mL | 12.0592 mL | 24.1185 mL | 60.2962 mL |
| 5 mM | 0.4824 mL | 2.4118 mL | 4.8237 mL | 12.0592 mL | |
| 10 mM | 0.2412 mL | 1.2059 mL | 2.4118 mL | 6.0296 mL | |
| 15 mM | 0.1608 mL | 0.8039 mL | 1.6079 mL | 4.0197 mL | |
| 20 mM | 0.1206 mL | 0.6030 mL | 1.2059 mL | 3.0148 mL | |
| 25 mM | 0.0965 mL | 0.4824 mL | 0.9647 mL | 2.4118 mL | |
| 30 mM | 0.0804 mL | 0.4020 mL | 0.8039 mL | 2.0099 mL | |
| 40 mM | 0.0603 mL | 0.3015 mL | 0.6030 mL | 1.5074 mL | |
| 50 mM | 0.0482 mL | 0.2412 mL | 0.4824 mL | 1.2059 mL | |
| 60 mM | 0.0402 mL | 0.2010 mL | 0.4020 mL | 1.0049 mL |
Palmitoyl serotonin Related Classifications
HY-131678 Related Classifications
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