PDE4-IN-26
PDE4-IN-26 (Compound A5) is an orally active and highly selective PDE4 inhibitor. PDE4-IN-26 has anti-inflammatory activity and can inhibit the phosphorylation of p38 MAPK. In mouse models of acute lung injury and chronic obstructive pulmonary disease, PDE4-IN-26 can improve pulmonary inflammation, injury and fibrosis, promote sputum secretion and relieve cough in mice. PDE4-IN-26 can be used for the research of lung injury-related diseases.
For research use only. We do not sell to patients.
- Formula: C22H18F2N4O3S
- Molecular Weight:456.47
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
PDE4A 89.7 nM (IC50) |
PDE4B 48.8 nM (IC50) |
PDE4D 5.9 nM (IC50) |
Chemical Information
-
Molecular Weight 456.47
-
Formula C22H18F2N4O3S
-
SMILES
FC(OC1=C(OCC2CC2)C=C(C3=NC4=C(N3)C=CC=C4C(NC5=NC=CS5)=O)C=C1)F
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PDE4-IN-26 Related Classifications
HY-172135 Related Classifications
Powered by Bioz