Petromurin C
Based on 1 publication(s) in Google Scholar
Petromurin C is a bisindolylbenzenoid compound isolated from the ascostromata of Petromycesmuricatus. Petromurin C induces protective autophagy and apoptosis in FLT3-ITD-positive AML.
For research use only. We do not sell to patients.
- CAS No.: 194608-29-2
- Formula: C26H24N2O5
- Molecular Weight:444.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Petromurin C
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| L02 | IC50 |
>100 μM
Compound: 3
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Cytotoxicity against human L02 cells assessed as cell growth inhibition incubated for 72 hrs by Cell Titer-Glo assay
Cytotoxicity against human L02 cells assessed as cell growth inhibition incubated for 72 hrs by Cell Titer-Glo assay
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[PMID: 37857311] |
| MV4-11 | IC50 |
12 μM
Compound: 3
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Cytotoxicity against human MV4-11 cells assessed as cell growth inhibition incubated for 72 hrs by Cell Titer-Glo assay
Cytotoxicity against human MV4-11 cells assessed as cell growth inhibition incubated for 72 hrs by Cell Titer-Glo assay
|
[PMID: 37857311] |
Chemical Information
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CAS No. 194608-29-2
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Molecular Weight 444.48
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Formula C26H24N2O5
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SMILES
COC1=C(C(OC)=C(C(C2=CNC3=C2C=CC=C3)=C1OC)OC)C4=CNC5=C4C=C(C=C5)O
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Structure Classification
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Initial Source
Petromyces muricatus
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Clin Sci
A novel epigenetic drug conjugating flavonoid and HDAC inhibitor confer suppression of acute myeloid leukemogenesis. [Abstract]2021 Jul 30;135(14):1751-1765. PMID: 34282832
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)