1. Anti-infection
  2. SARS-CoV
  3. PF-07321332

PF-07321332 

Cat. No.: HY-138687
Handling Instructions

PF-07321332 is a potent and orally active SARS-CoV 3C-like protease (3CLPRO) inhibitor . PF-07321332 targets to the SARS-CoV-2 virus and can be used for COVID-19 reseacrch.

For research use only. We do not sell to patients.

PF-07321332 Chemical Structure

PF-07321332 Chemical Structure

CAS No. : 2628280-40-8

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Description

PF-07321332 is a potent and orally active SARS-CoV 3C-like protease (3CLPRO) inhibitor . PF-07321332 targets to the SARS-CoV-2 virus and can be used for COVID-19 reseacrch[1].

IC50 & Target

IC50: 3CLPRO[1]

In Vitro

3CLPRO is responsible for cleaving polyproteins 1a and 1ab of SARS-CoV-2.1. Without the activity of the SARS-CoV-2 3CLPRO, nonstructural proteins (including proteases) cannot be released to perform their functions, inhibiting viral replication[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

499.53

Formula

C₂₃H₃₂F₃N₅O₄

CAS No.
SMILES

O=C(NCC1)[[email protected]@H]1C[[email protected]@H](C#N)NC([[email protected]@H]2[[email protected]]3([H])[[email protected]@](CN2C([[email protected]](C(C)(C)C)NC(C(F)(F)F)=O)=O)([H])C3(C)C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

PF-07321332PF07321332PF 07321332SARS-CoVSARS coronavirus3CLPROHIVSARS-CoV-2virusInhibitorinhibitorinhibit

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PF-07321332
Cat. No.:
HY-138687
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