PHD-1-IN-4
Based on 1 Customer Validation
PHD-1-IN-4 is a brain-penetrant PHD-1 inhibitor with an IC50 of 0.074 μM.
For research use only. We do not sell to patients.
- Purity: 99.94%
- CAS No.: 2009343-19-3
- Formula: C14H10N4
- Molecular Weight:234.26
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
PHD-1-IN-4 (Compound 39) potently inhibits purified PHD-1 enzyme with an IC50 of 0.074 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2009343-19-3
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Appearance Solid
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Molecular Weight 234.26
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Formula C14H10N4
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Color White to off-white
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SMILES
N#CC=1C=CC(C2=CC=CC3=NC=NN32)=C(C1)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (213.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2688 mL | 21.3438 mL | 42.6876 mL | 106.7190 mL |
| 5 mM | 0.8538 mL | 4.2688 mL | 8.5375 mL | 21.3438 mL | |
| 10 mM | 0.4269 mL | 2.1344 mL | 4.2688 mL | 10.6719 mL | |
| 15 mM | 0.2846 mL | 1.4229 mL | 2.8458 mL | 7.1146 mL | |
| 20 mM | 0.2134 mL | 1.0672 mL | 2.1344 mL | 5.3360 mL | |
| 25 mM | 0.1708 mL | 0.8538 mL | 1.7075 mL | 4.2688 mL | |
| 30 mM | 0.1423 mL | 0.7115 mL | 1.4229 mL | 3.5573 mL | |
| 40 mM | 0.1067 mL | 0.5336 mL | 1.0672 mL | 2.6680 mL | |
| 50 mM | 0.0854 mL | 0.4269 mL | 0.8538 mL | 2.1344 mL | |
| 60 mM | 0.0711 mL | 0.3557 mL | 0.7115 mL | 1.7787 mL | |
| 80 mM | 0.0534 mL | 0.2668 mL | 0.5336 mL | 1.3340 mL | |
| 100 mM | 0.0427 mL | 0.2134 mL | 0.4269 mL | 1.0672 mL |