PHD-IN-1
PHD-IN-1 (compound 80) is a potent inhibitor of PHD2,with an IC50 value of ≤5 nM. PHD-IN-1 shows EC50s of 2.5 μM in EPO Elisa assay both in Caco2-HIFla-HiBiT-clone-1 cells and Hep3B cells,respectively.
For research use only. We do not sell to patients.
- CAS No.: 2924182-31-8
- Formula: C24H23N7O2
- Molecular Weight:441.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: ≤5 nM (PHD2)[1]
Chemical Information
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CAS No. 2924182-31-8
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Molecular Weight 441.49
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Formula C24H23N7O2
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SMILES
OC1=C(C(NCC2=CN=C(C#N)C=C2)=O)N=CC3=C1C=CC(N4[C@]5([H])CN(C6CC6)[C@](C5)([H])C4)=N3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)