Physagulide J
Physagulide J is a kind of withanolides compound that can be isolated from Physalis angulata L.. Many kinds of active ingredients of Physalis angulata L. shows anti-inflammatory and anti-tumor activity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1496524-09-4
- 分子式: C30H40O7
- 分子量:512.63
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| 786-0 | IC50 |
0.39 μM
Compound: 17
|
Antiproliferative activity against human 786-0 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
Antiproliferative activity against human 786-0 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
|
[PMID: 27295506] |
| A498 | IC50 |
0.71 μM
Compound: 17
|
Antiproliferative activity against human A498 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
Antiproliferative activity against human A498 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
|
[PMID: 27295506] |
| ACHN | IC50 |
0.73 μM
Compound: 17
|
Antiproliferative activity against human ACHN cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
Antiproliferative activity against human ACHN cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
|
[PMID: 27295506] |
| CWR22R | IC50 |
0.9 μM
Compound: 17
|
Antiproliferative activity against human 22Rv1 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
Antiproliferative activity against human 22Rv1 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
|
[PMID: 27295506] |
| LNCaP C4-2B | IC50 |
0.49 μM
Compound: 17
|
Antiproliferative activity against human C4-2B cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
Antiproliferative activity against human C4-2B cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
|
[PMID: 27295506] |
| RAW264.7 | IC50 |
1.36 μM
Compound: 17
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
|
[PMID: 27295506] |
化学情報
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CAS 番号 1496524-09-4
-
分子量 512.63
-
分子式 C30H40O7
-
SMILES
CC(C[C@H]([C@H]([C@H]1C[C@@H]([C@]2([C@@H]3C[C@H]4O[C@]45CC=CC([C@@]5([C@H]3CC[C@@]21C)C)=O)O)OC(C)=O)C)O6)=C(C)C6=O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)