1. Phenols
    Others
  2. Pinostilbene

Pinostilbene 

Cat. No.: HY-N3059
Handling Instructions

Pinostilbene is a major metabolite of Pterostilbene. Pinostilbene exhibits inhibitory effects on colon cancer cells.

For research use only. We do not sell to patients.

Pinostilbene Chemical Structure

Pinostilbene Chemical Structure

CAS No. : 42438-89-1

Size Price Stock
5 mg USD 99 Ask For Quote & Lead Time
10 mg USD 168 Ask For Quote & Lead Time
20 mg USD 286 Ask For Quote & Lead Time

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Pinostilbene is a major metabolite of Pterostilbene. Pinostilbene exhibits inhibitory effects on colon cancer cells[1].

In Vitro

Pinostilbene (0- 40 μM; 24 hours, 48 hours) does not cause significant inhibition on the growth of normal colon cells[1].
Pinostilbene (20 μM, 40 μM; 24 hours, 48 hours) causes a significant and dose-dependent increase in the percentage of cells in S phase in both HCT116 and HT29 cells compared to the control cells[1].
Pinostilbene at μM also induces a modest increase of cell population in G2/M phase in HT29 cells[1].
Pinostilbene(20 μM, 40 μM; 24 hours, 48 hours) modulates expression of key signaling proteins related to cell proliferation and apoptosis[1].
Pinostilbene also acts as a resveratrol methylated derivative and displays protective effects against 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells[2].

Cell Viability Assay[1]

Cell Line: HCT116 cells, HT29 cells
Concentration: 24 hours, 48 hours
Incubation Time: 0-100 μM
Result: Inhibited the growth of two human colon cancer cells.

Apoptosis Analysis[1]

Cell Line: HCT116 cells, HT29 cells
Concentration: 20 μM, 40 μM
Incubation Time: 24 hours, 48 hours
Result: Caused a significant and dose-dependent increase in the percentage of cells in S phase.

Cell Viability Assay[1]

Cell Line: HCT116 cells
Concentration: 20 μM,40 μM
Incubation Time: 24 hours, 48 hours
Result: Significantly increased the expression levels of p53, Bax, cleaved caspase-3, cleaved PARP and p21Cip1/Waf1, while decreased the expression levels of cyclin E and p-Rb.
Molecular Weight

242.27

Formula

C₁₅H₁₄O₃

CAS No.

42438-89-1

SMILES

OC(C=C1)=CC=C1/C=C/C2=CC(OC)=CC(O)=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

PinostilbeneOthersPterostilbeneresveratrolcoloncancerInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product name:
Pinostilbene
Cat. No.:
HY-N3059
Quantity:
MCE Japan Authorized Agent: