Piperonyl butoxide-d9
Based on 1 Customer Validation
Piperonyl butoxide-d9 is the deuterium labeled Piperonyl butoxide.Piperonyl butoxide (ENT-14250) is a pesticide synergist and food additive. Piperonyl butoxide has adverse effects on reproduction, development and behavior in mice. Piperonyl butoxide can activate c-Jun and ATF-2 in mouse hepatocytes. Piperonyl butoxide is a liver cancer carcinogen in rats and mice.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.68%
- CAS 番号: 1329834-53-8
- 分子式: C19H21D9O5
- 分子量:347.49
-
保管条件:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
-
HY-126057S
(R)-Praziquantel-d11Antischistosomal Agent -
HY-B0261S
Meloxicam-d3Stable Isotope -
HY-B0777S
Moxidectin-d3Stable Isotope -
HY-33037
Phenazine-1-carboxylic acidFungal Inhibitor -
HY-W011235
Norfluoxetine hydrochlorideMetabolite of Fluoxetine -
HY-W019726
Dehydro NifedipineNifedipine Metabolite -
HY-125904
4-Hydroxyretinoic acidRetinoic Acid Derivative -
HY-116541
Acibenzolar-S-methylPlant Activator -
HY-B1953S
Thiacloprid-d4Stable Isotope -
HY-33037R
Phenazine-1-carboxylic acid (Standard)Fungal Inhibitor -
HY-137197
6β-Hydroxy dexamethasoneDexamethasone Metabolite -
HY-119649S
Flonicamid-15N,18OStable Isotope
Parasite アイソフォーム固有の製品をすべて表示
More
生物活性
製品説明
体外実験
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
アプリケーション
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
-
CAS 番号 1329834-53-8
-
非標識Cas 51-03-6
-
性状 Oil
-
分子量 347.49
-
分子式 C19H21D9O5
-
Color Colorless to light yellow
-
SMILES
[2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])OCCOCCOCC1=C(CCC)C=C(OCO2)C2=C1
-
別名
ENT-14250-d9
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
プロトコル
-
Liver Cancer Modeling
Liver cancer can be classified into primary liver cancer and secondary liver cancer. Secondary liver cancer is the metastatic liver cancer. Primary liver cancer includes hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC) and fibrolamellar HCC, of which HCC is the most common form, accounting for approximately 90% of primary liver cancers[1]. HCC mouse models include chemical agent-induced models, transplanted tumor models, and genetic engineered models.
純度とドキュメンテーション
-
データシート (266 KB)
-
SDS (459 KB)
- English - EN (459 KB)
- Français - FR (459 KB)
- Deutsch - DE (459 KB)
- Norwegian - NO (459 KB)
- Español - ES (459 KB)
- Swedish - SV (459 KB)
- Italian - IT (459 KB)
- Korean - KR (459 KB)
- Portuguese - PT (459 KB)
-
取扱説明書 (2659 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Muguruma M, et al. Piperonyl butoxide activates c-Jun and ATF-2 in the hepatocytes of mice. Arch Toxicol. 2008 Oct;82(10):749-53. [Content Brief]
[3]. Tanaka T, et al. Effects of piperonyl butoxide on exploratory behaviour in female mice. Toxicol Ind Health. 2019 Apr;35(4):314-323. [Content Brief]
[4]. Takahashi O, et al. Chronic toxicity studies of piperonyl butoxide in CD-1 mice: induction of hepatocellular carcinoma. Toxicology. 1997 Dec 26;124(2):95-103. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Piperonyl butoxide-d9 関連分類
HY-B1198S 関連分類
Powered by Bioz