PLAP-IN-1
PLAP-IN-1 is a selective PLAP inhibitor with an IC50 of 0.032 μM. PLAP-IN-1 acts as a tumor-targeting agent; its fluorescein-conjugated derivative specifically binds to PLAP-positive tumor cells in vitro and targets cervical cancer in mouse xenograft models. PLAP-IN-1 can be used in the research of cervical cancer and ovarian cancer.
For research use only. We do not sell to patients.
- CAS No.: 2857113-78-9
- Formula: C25H21Cl2N3O5
- Molecular Weight:514.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
PLAP-IN-1 (compound 16) potently inhibits purified PLAP with an IC50 of 32 nM, and exhibits high selectivity toward tissue-nonspecific alkaline phosphatase (TNAP)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2857113-78-9
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Molecular Weight 514.36
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Formula C25H21Cl2N3O5
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SMILES
ClC1=C(OC)C(Cl)=CC(C2=CC=CC(C[C@@H](NC(C3=NNC(C4=CC=C(C)O4)=C3)=O)C(O)=O)=C2)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PLAP-IN-1 Related Classifications
HY-139852 Related Classifications
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