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Cat. No.: HY-139652

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PLK1-IN-2

PLK1-IN-2 is a PLK1 kinase inhibitor with an IC₅₀ value of 0.384 μM.

For research use only. We do not sell to patients.

CAS No.: 2640254-52-8
Formula: C₂₄H₂₇FN₈OS
Molecular Weight:494.59

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

PLK1-IN-2 Chemical Structure

CAS No.: 2640254-52-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

PLK1-IN-2 is a PLK1 kinase inhibitor with an IC₅₀ value of 0.384 μM.

All Polo-like Kinase (PLK) Isoforms :

Chemical Information

CAS No. 2640254-52-8
Molecular Weight 494.59
Formula C₂₄H₂₇FN₈OS
SMILES

CN(CC1)CCN1C2=CC=C(NC3=NC(N(C4=NC(N=S(C)(C)=O)=CC=C4)C=C5F)=C5C=N3)C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kargbo RB. Modulation of KRAS Mutant by Inhibiting PLK1 Kinase in Cancer Therapeutics. ACS Med Chem Lett. 2021 Sep 15;12(10):1514-1516. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Chemical Information
Purity & Documentation
References

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PLK1-IN-2

Volasertib

Onvansertib

TAK-960

Centrinone

GSK461364

HMN-214

Volasertib trihydrochloride

MLN0905

HMN-176

Centrinone-B

Poloxin

Ro3280

All Polo-like Kinase (PLK) Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Bioz

PLK1-IN-2

Volasertib

Onvansertib

TAK-960

Centrinone

GSK461364

HMN-214

Volasertib trihydrochloride

MLN0905

HMN-176

Centrinone-B

Poloxin

Ro3280

All Polo-like Kinase (PLK) Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

PLK1-IN-2 Related Classifications

HY-139652 Related Classifications

Bioz