(+)-Hannokinol
(+)-Hannokinol can be isolated from AMOMUM TSAO-KO (ginger family) fruit. (+)-Hannokinol inhibits lipopolysaccharide-induced nitric oxide production in BV2 microglia.
For research use only. We do not sell to patients.
- CAS No.: 408324-76-5
- Formula: C19H24O4
- Molecular Weight:316.39
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| B16-4A5 | IC50 |
>10 μM
Compound: 9
|
Antimelanogenic activity in mouse B16-4A5 cells assessed as inhibition of theophylline-induced melanin production after 72 hrs by spectrophotometry relative to control
Antimelanogenic activity in mouse B16-4A5 cells assessed as inhibition of theophylline-induced melanin production after 72 hrs by spectrophotometry relative to control
|
[PMID: 23910596] |
| HL-60 | IC50 |
>10 μg/mL
Compound: 9a
|
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
|
[PMID: 11908966] |
| HSC-2 | IC50 |
231 μg/mL
Compound: 9a
|
Cytotoxicity against human HSC2 cells by MTT assay
Cytotoxicity against human HSC2 cells by MTT assay
|
[PMID: 11908966] |
| RAW264.7 | IC50 |
>100 μM
Compound: 7a
|
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells after 24 hrs by Griess reaction based spectrophotometry
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells after 24 hrs by Griess reaction based spectrophotometry
|
[PMID: 21807513] |
Chemical Information
-
CAS No. 408324-76-5
-
Molecular Weight 316.39
-
Formula C19H24O4
-
SMILES
OC(C=C1)=CC=C1CC[C@@H](O)C[C@H](O)CCC2=CC=C(C=C2)O
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)