2. PROTAC Epigenetics Cell Cycle/DNA Damage
  3. HDAC PROTACs
  4. PRO-HD1

PRO-HD1 is a PROTAC HDAC6 degrader. PRO-HD1 degrades HDAC6 in A549 cells, and inhibits proliferation of Jurkat cells (IC50: 5.8 μM).

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PRO-HD1

PRO-HD1 화학구조

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PRO-HD1 Related Antibodies

Top Publications Citing Use of Products

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von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

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제품 설명

PRO-HD1 is a PROTAC HDAC6 degrader. PRO-HD1 degrades HDAC6 in A549 cells, and inhibits proliferation of Jurkat cells (IC50: 5.8 μM)[1].

분자량

649.76

화학식

C36H35N5O5S
SMILES

S=C1N(CC2=CC=C(C3=CC=C(CNCCCCNC4=CC=CC(C(N5C6CCC(NC6=O)=O)=O)=C4C5=O)C=C3)C=C2)C=CC=C1O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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PRO-HD1 Related Classifications

  • 몰농도 계산기

  • 농도 희석 계산기

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PRO-HD1HDACPROTACsHistone deacetylasesA549Jurkat cellInhibitorinhibitorinhibit

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상품명:
PRO-HD1
Cat. No.:
HY-155396
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