Prometryn-d14
Based on 1 Customer Validation
Prometryn-d14 is the deuterium labeled Prometryn. Prometryn is a triazine herbicide. Prometryn induces apoptosis and cell cycle arrest. Prometryn induces oxidative stress, DNA damage and autophagy-related gene expression, and non-specific immunity gene expression. Prometryn can be used for the research of herbicide, hepatopancreas injury, and intestinal stress and intestinal barrier dysfunction.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.89%
- CAS. Nr.: 1202864-57-0
- Formel: C10H5D14N5S
- Molecular Weight:255.44
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Speicherung:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Protokoll
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
- RT-PCR
- RNA extraction experimental
- Annexin V plus membrane-impermeant dye apoptosis staining
- BrdU Incorporation Assay
- ROS/oxidative-stress fluorescent staining
- Protocol for Cell Cycle
- Real Time qPCR (Q-PCR)
- Detection of Apoptosis
- TUNEL staining for apoptotic DNA fragmentation
- Flow cytometric DNA-content cell-cycle staining
- Autophagy
- Apoptosis Solutions
- Lysosome and acidic-vesicle live-cell staining
- Macroautophagy Solutions
- Genotoxicity/Mutagenicity Study
Anwendung
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 1202864-57-0
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Unlabeled CAS 7287-19-6
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Appearance Solid
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Molecular Weight 255.44
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Formel C10H5D14N5S
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Color White to off-white
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SMILES
[2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])NC1=NC(SC)=NC(NC(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])=N1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Reinheit & Dokumentation
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Data Sheet (272 KB)
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SDS (537 KB)
- English - EN (537 KB)
- Français - FR (537 KB)
- Deutsch - DE (537 KB)
- Norwegian - NO (537 KB)
- Español - ES (537 KB)
- Swedish - SV (537 KB)
- Italian - IT (537 KB)
- Korean - KR (537 KB)
- Portuguese - PT (537 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Liu Q, et al. Prometryn induces apoptotic cell death through cell cycle arrest and oxidative DNA damage. Toxicol Res (Camb). 2019;8(6):833-841. Published 2019 Jul 26. [Content Brief]
[2]. Huang P, et al. Effects of prometryn on oxidative stress, immune response and apoptosis in the hepatopancreas of Eriocheir sinensis (Crustacea: Decapoda). Ecotoxicol Environ Saf. Published online June 23, 2023. [Content Brief]
[3]. Huang P, et al. Prometryn exposure disrupts the intestinal health of Eriocheir sinensis: Physiological responses and underlying mechanism. Comp Biochem Physiol C Toxicol Pharmacol. 2024;277:109820. [Content Brief]
[4]. Min N, et al. Developmental toxicity of prometryn induces mitochondrial dysfunction, oxidative stress, and failure of organogenesis in zebrafish (Danio rerio). J Hazard Mater. 2023;443(Pt A):130202. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Prometryn-d14 Related Classifications
HY-121324S Related Classifications
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