2. PROTAC Epigenetics
  3. PROTACs Epigenetic Reader Domain
  4. PROTAC BRD4 Degrader-26

PROTAC BRD4 Degrader-26 (PROTAC-2) is a photo-regulated PROTAC, which degrades 80% BRD4 at 1 μM by using photocleavable linker. PROTAC BRD4 Degrader-26 will be deactivated by UV light. (Pink: ligand for target protein BRD4 ligand 6 (HY-161651); Black: linker (HY-161653); Blue: E3 ligase ligand Thalidomide 4-fluoride (HY-41547))

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PROTAC BRD4 Degrader-26

PROTAC BRD4 Degrader-26 화학구조

CAS No. : 3050769-37-1

사이즈 재고
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This product is a controlled substance and not for sale in your territory.

PROTAC BRD4 Degrader-26 Related Antibodies

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von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

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제품 설명

PROTAC BRD4 Degrader-26 (PROTAC-2) is a photo-regulated PROTAC, which degrades 80% BRD4 at 1 μM by using photocleavable linker. PROTAC BRD4 Degrader-26 will be deactivated by UV light. (Pink: ligand for target protein BRD4 ligand 6 (HY-161651); Black: linker (HY-161653); Blue: E3 ligase ligand Thalidomide 4-fluoride (HY-41547))[1]

IC50 & Target

BRD4

 

분자량

965.43

화학식

C46H45ClN10O10S
CAS No.
SMILES

O=C(C1=C(NCCCOC2=CC(COC(NCCCNC(C[C@H]3C4=NN=C(C)N4C(SC(C)=C5C)=C5C(C6=CC=C(Cl)C=C6)=N3)=O)=O)=C([N+]([O-])=O)C=C2)C=CC=C17)N(C8C(NC(CC8)=O)=O)C7=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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PROTAC BRD4 Degrader-26 Related Classifications

  • 몰농도 계산기

  • 농도 희석 계산기

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC BRD4 Degrader-263050769-37-1PROTACsEpigenetic Reader DomainMCF-7UV lightphotocleavableInhibitorinhibitorinhibit

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상품명:
PROTAC BRD4 Degrader-26
Cat. No.:
HY-161650
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