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Cat. No.: HY-181623

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PROTAC BTK degrader-14

PROTAC BTK degrader-14 (compound 112) is a PROTAC protein degrader targeting BTK. PROTAC BTK degrader-14 can be used for the research of cancer.
(Pink: Btk ligand (HY-181624); Blue: Cereblon ligand (HY-W245311); Black: linker).

For research use only. We do not sell to patients.

CAS No.: 3114684-06-6
Formula: C₄₆H₅₄N₁₄O₃
Molecular Weight:851.01

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

PROTAC BTK degrader-14 Chemical Structure

CAS No.: 3114684-06-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

PROTAC BTK degrader-14 (compound 112) is a PROTAC protein degrader targeting BTK. PROTAC BTK degrader-14 can be used for the research of cancer^[1]. (Pink: Btk ligand (HY-181624); Blue: Cereblon ligand (HY-W245311); Black: linker).

All PROTACs Isoforms :

Chemical Information

CAS No. 3114684-06-6
Molecular Weight 851.01
Formula C₄₆H₅₄N₁₄O₃
SMILES

O=C(CC1)NC(N1C2=CC=C(N3CCC(CN4CCN(C5=CC=C(C(N=C6C7=CC=C([C@H](NC(C8=NN(C(C)(C)C)N=N8)=O)C)C(C)=C7)=CN9C6=CC=N9)C=N5)CC4)CC3)C=C2)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Jiantao HU, et al. Btk degrader and use thereof. WO2026021570A1. 2025.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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