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PROTAC SMARCA2 degrader-12

SMARCA2 degrader-13 (compound I-406) is a PROTAC degrader targeting SMARCA2; it degrades SMARCA2 proteins in A549 cells with an DC50 <100 nM, and a maximum degradation rate (Dmax%) >90 after 24 h of treatment.
(Pink: SMARCA2 ligand (HY-159545); Blue: VHL ligand (HY-163951); Black: linker (HY-W006635)).

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  • CAS 番号: 2568277-42-7
  • 分子式: C49H57N11O5S
  • 分子量:912.11
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • PROTAC SMARCA2 degrader-12 Chemical Structure
    PROTAC SMARCA2 degrader-12 構造式
CAS 番号: 2568277-42-7
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  • PROTAC SMARCA2 degrader-12 Chemical Structure
    PROTAC SMARCA2 degrader-12 Chemical Structure
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  • PROTAC SMARCA2 degrader-12