PTCA
Based on 1 Customer Validation
PTCA is a potent Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα) ligand with a pKi value of 7.2.
For research use only. We do not sell to patients.
- Purity: 99.72%
- CAS No.: 871326-47-5
- Formula: C10H5Cl2NO2S
- Molecular Weight:274.12
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 871326-47-5
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Appearance Solid
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Molecular Weight 274.12
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Formula C10H5Cl2NO2S
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Color White to off-white
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SMILES
O=C(C1=CSC(C2=C(Cl)C=CC=C2Cl)=N1)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (364.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6480 mL | 18.2402 mL | 36.4804 mL | 91.2009 mL |
| 5 mM | 0.7296 mL | 3.6480 mL | 7.2961 mL | 18.2402 mL | |
| 10 mM | 0.3648 mL | 1.8240 mL | 3.6480 mL | 9.1201 mL | |
| 15 mM | 0.2432 mL | 1.2160 mL | 2.4320 mL | 6.0801 mL | |
| 20 mM | 0.1824 mL | 0.9120 mL | 1.8240 mL | 4.5600 mL | |
| 25 mM | 0.1459 mL | 0.7296 mL | 1.4592 mL | 3.6480 mL | |
| 30 mM | 0.1216 mL | 0.6080 mL | 1.2160 mL | 3.0400 mL | |
| 40 mM | 0.0912 mL | 0.4560 mL | 0.9120 mL | 2.2800 mL | |
| 50 mM | 0.0730 mL | 0.3648 mL | 0.7296 mL | 1.8240 mL | |
| 60 mM | 0.0608 mL | 0.3040 mL | 0.6080 mL | 1.5200 mL | |
| 80 mM | 0.0456 mL | 0.2280 mL | 0.4560 mL | 1.1400 mL | |
| 100 mM | 0.0365 mL | 0.1824 mL | 0.3648 mL | 0.9120 mL |