Chelidonine Induces Caspase-Dependent and Caspase-Independent Cell Death through G2/M Arrest in the T98G Human Glioblastoma Cell Line

  • Evid Based Complement Alternat Med. 2019 May 26;2019:6318179. doi: 10.1155/2019/6318179.
Yeon-Kyeong Lee  1 ,  Ki Won Lee  1 ,  Minju Kim  1 ,  Yerin Lee  1 ,  Jiyun Yoo  1  2 ,  Cheol Hwangbo  2 ,  Ki Hun Park  1 ,  Kwang Dong Kim  1  2  3
Affiliations
  • 1. Division of Applied Life Science (BK21Plus), Gyeongsang National University, Jinju 660-701, Republic of Korea.
  • 2. Division of Life Science, Gyeongsang National University, Jinju 660-701, Republic of Korea.
  • 3. PMBBRC, Gyeongsang National University, Jinju 660-701, Republic of Korea.
Abstract

Chelidonium majus L. (family Papaveraceae), commonly known as greater celandine or tetterwort, has been reported to have Antibacterial and Anticancer effects and chelidonine is known as a functional metabolite extracted from C.

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