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Art. -Nr.: HY-111407BR

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(R)-MK-8353 (Standard)

Name: (R)-MK-8353 (Standard)
Brand: MedChemExpress
SKU: HY-111407BR
Availability: PreOrder

(Synonyms: (R)-SCH900353 (Standard))

(R)-MK-8353 (Standard) is the analytical standard of (R)-MK-8353 (HY-111407B). This product is intended for research and analytical applications. (R)-MK-8353 ((R)-SCH900353) is the R-enantiomer of MK-8353 (HY-111407). MK-8353 (SCH900353) is a potent, selective and orally active ERK1 and ERK2 inhibitor with IC₅₀s of 23.0 nM and 8.8 nM, respectively.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 2748457-30-7
Formel: C₃₇H₄₁N₉O₃S
Molecular Weight:691.84

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

(R)-MK-8353 (Standard) Chemical Structure

CAS. Nr.: 2748457-30-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Product Information
- Information
- Anwendung
Chemical Information
Reinheit & Dokumentation
Calculators
Help & FAQs
Classifications
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Product Information

Information

Anwendung

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS. Nr. 2748457-30-7
Molecular Weight 691.84
Formel C₃₇H₄₁N₉O₃S
SMILES

O=C([C@]1(SC)CN(CC(N2CC=C(C3=CC=C(C4=NN(C)C=N4)C=C3)CC2)=O)CC1)NC5=CC6=C(NN=C6C7=CC=C(OC(C)C)N=C7)C=C5
Synonyms

(R)-SCH900353 (Standard)
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Stergios J Moschos, et al. Development of MK-8353, an orally administered ERK1/2 inhibitor, in patients with advanced solid tumors. JCI Insight. 2018 Feb 22;3(4):e92352. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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