(R)-Norfluoxetine
(R)-Norfluoxetine is the (R)-enantiomer of Norfluoxetine (HY-135556). (R)-Norfluoxetine is a potent serotonin re-uptake inhibitor, with a Ki of 13 nM. (R)-Norfluoxetine can be used for the research of depression.
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- CAS No.: 130194-43-3
- 화학식: C16H16F3NO
- 분자량:295.30
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
13 nM
Compound: (R)-3
|
Inhibition of [3H]5HT from human recombinant SERT expressed in HEK293 cells
Inhibition of [3H]5HT from human recombinant SERT expressed in HEK293 cells
|
[PMID: 19014888] |
| HEK293 | IC50 |
1995 nM
Compound: (R)-3
|
Inhibition of [3H]NE from human recombinant NET expressed in HEK293 cells
Inhibition of [3H]NE from human recombinant NET expressed in HEK293 cells
|
[PMID: 19014888] |
| HEK293 | IC50 |
7133 nM
Compound: (R)-3
|
Inhibition of [3H]DA from human recombinant DAT expressed in HEK293 cells
Inhibition of [3H]DA from human recombinant DAT expressed in HEK293 cells
|
[PMID: 19014888] |
Chemical Information
-
CAS No. 130194-43-3
-
분자량 295.30
-
화학식 C16H16F3NO
-
SMILES
FC(F)(F)C1=CC=C(O[C@H](CCN)C2=CC=CC=C2)C=C1
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)