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Cat. No.: HY-N21822

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(+)-(R)-Ribalinine

Name: (+)-(R)-Ribalinine
Brand: MedChemExpress
SKU: HY-N21822
Availability: PreOrder

(Synonyms: Folifine)

(+)-(R)-Ribalinine (Folifine) is an inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with an IC₅₀ value of 153.31 μM against electric eel acetylcholinesterase and an IC₅₀ value of 12.99 μM against equine butyrylcholinesterase.

For research use only. We do not sell to patients.

CAS No.: 62928-56-7
Formula: C₁₅H₁₇NO₃
Molecular Weight:259.30

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

(+)-(R)-Ribalinine Chemical Structure

CAS No.: 62928-56-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Protocols (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target

^[1]

electric eel AChE

153.31 μM (IC₅₀)

equine serum BChE

12.99 μM (IC₅₀)

All Cholinesterase (ChE) Isoforms :

AChE
BChE

In Vitro

(+)-(R)-Ribalinine (Compound 6) (100-1000 μM; 30 min) inhibits electric eel acetylcholinesterase with an IC₅₀ of 153.31 μM^[1].
(+)-(R)-Ribalinine (12.5-100 μM; 30 min) inhibits horse butyrylcholinesterase with an IC₅₀ of 12.99 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.

Chemical Information

CAS No. 62928-56-7
Molecular Weight 259.30
Formula C₁₅H₁₇NO₃
SMILES

CC1(C)OC2=C(C(C3=CC=CC=C3N2C)=O)C[C@H]1O
Synonyms

Folifine
Structure Classification
- Alkaloids
- Other Alkaloids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Sultana N, et al. A new fatty ester and a new triterpene from Skimmia laureola. Natural product research. 2008 Jan 10;22(1):37-47. [Content Brief]

[2]. Derek R. et al. Synthesis and absolute stereochemistry assignment of enantiopure dihydrofuro- and dihydropyrano-quinoline alkaloids. J. Chem. Soc., Perkin Trans. 1 2000; 29 (20): 3397-3405.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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