1. Others Membrane Transporter/Ion Channel Autophagy
  2. Isotope-Labeled Compounds Monoamine Transporter Autophagy
  3. Reserpine-d9

Reserpine-d9 is the deuterium labeled Reserpine. Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).

For research use only. We do not sell to patients.

Reserpine-d<sub>9</sub> Chemical Structure

Reserpine-d9 Chemical Structure

CAS No. : 84759-11-5

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1 mg USD 660 In-stock
5 mg USD 1980 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Reserpine-d9 is the deuterium labeled Reserpine. Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

617.73

Formula

C33H31D9N2O9

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

COC([C@H]1[C@@]2([H])C[C@]3([H])C4=C(CCN3C[C@@]2([H])C[C@H]([C@@H]1OC)OC(C5=CC(OC([2H])([2H])[2H])=C(C(OC([2H])([2H])[2H])=C5)OC([2H])([2H])[2H])=O)C6=CC=C(OC)C=C6N4)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 33.33 mg/mL (53.96 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6188 mL 8.0942 mL 16.1883 mL
5 mM 0.3238 mL 1.6188 mL 3.2377 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥97.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6188 mL 8.0942 mL 16.1883 mL 40.4708 mL
5 mM 0.3238 mL 1.6188 mL 3.2377 mL 8.0942 mL
10 mM 0.1619 mL 0.8094 mL 1.6188 mL 4.0471 mL
15 mM 0.1079 mL 0.5396 mL 1.0792 mL 2.6981 mL
20 mM 0.0809 mL 0.4047 mL 0.8094 mL 2.0235 mL
25 mM 0.0648 mL 0.3238 mL 0.6475 mL 1.6188 mL
30 mM 0.0540 mL 0.2698 mL 0.5396 mL 1.3490 mL
40 mM 0.0405 mL 0.2024 mL 0.4047 mL 1.0118 mL
50 mM 0.0324 mL 0.1619 mL 0.3238 mL 0.8094 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Reserpine-d9
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HY-N0480S
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