RIPK1-IN-14
RIPK1-IN-14 (Compound 41) is a potent inhibitor of RIPK1 with an IC50 value of 92 nM. RIPK1-IN-14 shows a significant anti-necroptotic effect in a necroptosis model in U937 cells.
For research use only. We do not sell to patients.
- CAS No.: 2919964-79-5
- Formula: C25H25F2N3O2
- Molecular Weight:437.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
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RIPK1 |
Chemical Information
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CAS No. 2919964-79-5
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Molecular Weight 437.48
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Formula C25H25F2N3O2
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SMILES
CN1C=CC2=CC=C(C=C21)C(N3CCC4(CCN(C4=O)CC5=CC(F)=CC=C5F)CC3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RIPK1-IN-14 Related Classifications
HY-146758 Related Classifications
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