RIPK1-IN-31
RIPK1-IN-31 (Compound 36) is a selective allosteric modulator of RIPK1 (receptor-interacting protein kinase 1) with an IC50 value of 16 nM. RIPK1-IN-31 is promising for research of infectious, autoimmune, and neurodegenerative diseases.
For research use only. We do not sell to patients.
- CAS No.: 2857845-45-3
- Formula: C15H15F2N3O2
- Molecular Weight:307.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
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hRIP1 16 nM (IC50) |
Chemical Information
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CAS No. 2857845-45-3
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Molecular Weight 307.30
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Formula C15H15F2N3O2
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SMILES
O=C(C(C(F)F)(C)C)N1C[C@H]2OC3=C(C#N)C=NC=C3[C@@H]1C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RIPK1-IN-31 Related Classifications
HY-173574 Related Classifications
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