1. GPCR/G Protein
    Neuronal Signaling
  2. Dopamine Receptor
  3. Ropinirole-d4 hydrochloride

Ropinirole-d4 hydrochloride (Synonyms: SKF 101468-d4 hydrochloride)

Cat. No.: HY-B0623AS
Handling Instructions

Ropinirole-d4 (SKF 101468-d4) hydrochloride is the deuterium labeled Ropinirole hydrochloride. Ropinirole hydrochloride is a potent D3/D2 receptor agonist with a Ki of 29 nM for D2 receptor. Ropinirole hydrochloride has pEC50s of 7.4, 8.4 and 6.8 for hD2, hD3 and hD4 receptors, respectively. Ropinirole hydrochloride has no affinity for the D1 receptors. Ropinirole hydrochloride has the potential for Parkinson's disease.

For research use only. We do not sell to patients.

Ropinirole-d4 hydrochloride Chemical Structure

Ropinirole-d4 hydrochloride Chemical Structure

CAS No. : 1330261-37-4

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Description

Ropinirole-d4 (SKF 101468-d4) hydrochloride is the deuterium labeled Ropinirole hydrochloride. Ropinirole hydrochloride is a potent D3/D2 receptor agonist with a Ki of 29 nM for D2 receptor. Ropinirole hydrochloride has pEC50s of 7.4, 8.4 and 6.8 for hD2, hD3 and hD4 receptors, respectively. Ropinirole hydrochloride has no affinity for the D1 receptors. Ropinirole hydrochloride has the potential for Parkinson's disease[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

300.86

Formula

C16H21D4ClN2O

CAS No.
SMILES

C(CN(C(CC)([2H])[2H])C(CC)([2H])[2H])C1=C2C(NC(=O)C2)=CC=C1.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Ropinirole-d4 hydrochloride
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