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Cat. No.: HY-130052

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Rosellichalasin

Rosellichalasin is an antibacterial agent isolated from the endophytic fungus Aspergillus flavipes Y-62. Rosellichalasin exhibits antibacterial activity.

For research use only. We do not sell to patients.

CAS No.: 123452-64-2
Formula: C₂₈H₃₃NO₅
Molecular Weight:463.57

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Rosellichalasin Chemical Structure

CAS No.: 123452-64-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

Rosellichalasin is an antibacterial agent isolated from the endophytic fungus Aspergillus flavipes Y-62. Rosellichalasin exhibits antibacterial activity^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
SUP-T1	CC₅₀	98.6 μM Compound: 7	Cytotoxicity against human SupT1 cells assessed as decrease in cell viability after 48 hrs by CCK-8 assay Cytotoxicity against human SupT1 cells assessed as decrease in cell viability after 48 hrs by CCK-8 assay	[PMID: 29016131]

In Vitro

Rosellichalasin inhibits the growth of Klebsiella pneumoniae, Pseudomonas aeruginosa, Escherichia coli, and Bacillus subtilis, with a MIC of 32 µg/mL for all strains^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 123452-64-2
Molecular Weight 463.57
Formula C₂₈H₃₃NO₅
SMILES

O=C1C/C=C(C)\C([C@@H](C)C/C=C/[C@@]2([H])[C@]([H])(O3)[C@@]3(C)[C@@H](C)[C@@]([H])([C@H](CC4=CC=CC=C4)NC5=O)[C@]25O1)=O
Structure Classification
- Alkaloids
- Other Alkaloids
Initial Source
- Microorganisms
Rosellinia necatrix
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Akhter N, et al. Isolation and structure determination of a new indene derivative from endophytic fungus Aspergillus flavipes Y-62. Nat Prod Res. 2019 Oct;33(20):2939-2944. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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