2. Anti-infection
  3. Bacterial
  4. Roseoflavin

Roseoflavin, a natural pigment originally isolated from Streptomyces davawensis, is an antimetabolite analog of Riboflavin and flavin mononucleotide that has antimicrobial properties.

For research use only. We do not sell to patients.

Roseoflavin Chemical Structure

Roseoflavin Chemical Structure

CAS No. : 51093-55-1

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Based on 1 publication(s) in Google Scholar

Roseoflavin Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

Roseoflavin, a natural pigment originally isolated from Streptomyces davawensis, is an antimetabolite analog of Riboflavin and flavin mononucleotide that has antimicrobial properties[1].

In Vitro

Roseoflavin, a chemical analog of flavin mononucleotide (FMN) and riboflavin that has antimicrobial activity, can directly bind to FMN riboswitch (Kd~100 nM) aptamers and downregulate the expression of an FMN riboswitch-lacZ reporter gene in B. subtilis[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Roseoflavin Related Antibodies
Molecular Weight

405.41

Formula

C18H23N5O6
CAS No.
Appearance

Solid

Color

Brown to reddish brown

SMILES

O=C(N1)C2=NC3=CC(C)=C(C=C3N(C2=NC1=O)C[C@@H]([C@@H]([C@@H](CO)O)O)O)N(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (123.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4666 mL 12.3332 mL 24.6664 mL
5 mM 0.4933 mL 2.4666 mL 4.9333 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.05%

COA (256 KB) HNMR (252 KB) RP-HPLC (305 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4666 mL 12.3332 mL 24.6664 mL 61.6660 mL
5 mM 0.4933 mL 2.4666 mL 4.9333 mL 12.3332 mL
10 mM 0.2467 mL 1.2333 mL 2.4666 mL 6.1666 mL
15 mM 0.1644 mL 0.8222 mL 1.6444 mL 4.1111 mL
20 mM 0.1233 mL 0.6167 mL 1.2333 mL 3.0833 mL
25 mM 0.0987 mL 0.4933 mL 0.9867 mL 2.4666 mL
30 mM 0.0822 mL 0.4111 mL 0.8222 mL 2.0555 mL
40 mM 0.0617 mL 0.3083 mL 0.6167 mL 1.5416 mL
50 mM 0.0493 mL 0.2467 mL 0.4933 mL 1.2333 mL
60 mM 0.0411 mL 0.2056 mL 0.4111 mL 1.0278 mL
80 mM 0.0308 mL 0.1542 mL 0.3083 mL 0.7708 mL
100 mM 0.0247 mL 0.1233 mL 0.2467 mL 0.6167 mL
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Roseoflavin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Roseoflavin51093-55-1BacterialresistantbacteriaantimicrobialpigmentanalogRNAligandriboswitchInhibitorinhibitorinhibit

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