2. Neuronal Signaling
  3. Huntingtin
  4. Rovanersen sodium

Rovanersen sodium  (Synonyms: WVE-120101 sodium)

Cat. No.: HY-132593A Purity: 95.58%
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Rovanersen sodium is an antisense oligonucleotide that specifically targets mutated mRNA copies of the huntington (HTT) gene without affecting healthy mRNA of HTT gene, thereby preventing the production of faulty Huntingtin protein. Rovanersen sodium can be used for huntington’s disease research.

For research use only. We do not sell to patients.

DNA,d(rGm-[P(S)]-sp-rGm-rCm-rAm-rCm-[P(S)]-sp-A-[P(S)]-sp-A-[P(S)]-sp-G-[P(S)]-sp-G-[P(S)]-sp-G-[P(S)]-sp-C-[P(S)]-sp-A-[P(S)]-sp-C-[P(R)]-sp-A-[P(S)]-sp-G-[P(S)]-sp-rAm-rCm-rUm-rUm-[P(S)]-sp-rCm), sodium salt

Rovanersen sodium Chemical Structure

CAS No. : 2231347-41-2

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Based on 1 publication(s) in Google Scholar

Other Forms of Rovanersen sodium:

Rovanersen sodium Related Antibodies

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Description

Rovanersen sodium is an antisense oligonucleotide that specifically targets mutated mRNA copies of the huntington (HTT) gene without affecting healthy mRNA of HTT gene, thereby preventing the production of faulty Huntingtin protein. Rovanersen sodium can be used for huntington’s disease research[1].

Molecular Weight

6617 (free acid)

Formula

C202H240N82Na19O111P19S13
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[Rovanersen (sodium)]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (Need ultrasonic)

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This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
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Rovanersen sodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rovanersen2231347-41-2WVE-120101WVE120101WVE 120101Huntingtinantisenseoligonucleotidehuntington’sdiseaseInhibitorinhibitorinhibit

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