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Cat. No.: HY-144383

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RXR antagonist 2

RXR antagonist 2 (compound 6b) is a potent antagonist of RXR with a K_i and K_d of 0.391 and 0.281 μM. RXR antagonist 2 has the potential for the research of RXR related diseases.

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CAS No.: 3010910-41-2
Formule: C₂₉H₃₅F₃N₂O₃
Masse moléculaire:516.60

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

RXR antagonist 2 Chemical Structure

CAS No.: 3010910-41-2

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Description

RXR antagonist 2 (compound 6b) is a potent antagonist of RXR with a K_i and K_d of 0.391 and 0.281 μM. RXR antagonist 2 has the potential for the research of RXR related diseases^[1].

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Chemical Information

CAS No. 3010910-41-2
Masse moléculaire 516.60
Formule C₂₉H₃₅F₃N₂O₃
SMILES

FC(F)(F)C1=NC2=C(C=CC(C(O)=O)=C2)N1C3=CC(C(C)(CCC4(C)C)C)=C4C=C3OCCCCCC
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Watanabe M, et al. Increased Molecular Flexibility Widens the Gap between Ki and Kd values in Screening for Retinoid X Receptor Modulators. ACS Med Chem Lett. 2022 Jan 21;13(2):211-217. [Content Brief]

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Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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RXR antagonist 2

Voir tous les produits spécifiques à Isoform RAR/RXR

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

RXR antagonist 2 Related Classifications

HY-144383 Related Classifications