2. GPCR/G Protein
  3. Guanylate Cyclase
  4. S-3448

S-3448 is a derivative of Ataciguat (HY-17500). S-3448 is a Soluble guanylate cyclase (sGC) agonist. S-3448 activates both the haem-containing and the haem-deficient form of sGC without depending on NO and heme. S-3448 can be used for cardiovascular diseases such as arterial hypertension and pulmonary hypertension research.

For research use only. We do not sell to patients.

S-3448

S-3448 Chemical Structure

CAS No. : 254877-04-8

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S-3448 Related Antibodies

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Description

S-3448 is a derivative of Ataciguat (HY-17500). S-3448 is a Soluble guanylate cyclase (sGC) agonist. S-3448 activates both the haem-containing and the haem-deficient form of sGC without depending on NO and heme. S-3448 can be used for cardiovascular diseases such as arterial hypertension and pulmonary hypertension research[1].

Molecular Weight

612.14

Formula

C25H26ClN3O7S3
CAS No.
SMILES

O=C(NC1=CC=C(S(=O)(N2CCSCC2)=O)C=C1)C3=CC(OC)=C(OC)C=C3NS(=O)(C4=CC=C(Cl)C=C4)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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S-3448 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

S-3448254877-04-8S3448S 3448Guanylate CyclaseAtaciguatSoluble guanylate cyclasesGChaemNOarterial hypertensionpulmonary hypertensionInhibitorinhibitorinhibit

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HY-124074
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