(S)-6-Methylnicotine
Based on 1 Customer Validation
(S)-6-Methylnicotine is a nicotinic acetylcholine receptor (nAChR) agonist that exhibits agonistic activity on isolated guinea pig ileum. (S)-6-Methylnicotine produces sensations identical to those of nicotine and has addictive potential. (S)-6-Methylnicotine shows high cytotoxicity against human bronchial epithelial cells and exerts a weak effect on the upregulation of lung cancer-related proteins. (S)-6-Methylnicotine can be used in the research of respiratory system diseases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 13270-56-9
- 分子式: C11H16N2
- 分子量:176.26
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
生物活性
(S)-6-Methylnicotine is a naturally occurring minor tobacco alkaloid present in additive-free cured leaf tobaccos, smokeless tobaccos, and domestic/foreign/Nigerian cigarettes at an all-sample average level of 0.32 µg per g of tobacco material[1].
(S)-6-Methylnicotine confirms presence in Sweet Spearmint, Blue Razz Ice, and Mango Grapefruit Spree Bar e-liquids, with mass accuracy within 7 ppm of the theoretical [M+H]+ ion value[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 13270-56-9
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性状 Liquid (Density: 1.016±0.06 g/cm3)
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分子量 176.26
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分子式 C11H16N2
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Color Colorless to light yellow
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SMILES
CN1[C@H](C2=CN=C(C)C=C2)CCC1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (394 KB)
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- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Pankow JF, et al. Levels of the nicotine analog 6-methyl nicotine as a naturally formed tobacco alkaloid in tobacco and tobacco products. Scientific reports. 2025 May 23;15(1):17945. [Content Brief]
[2]. Jordt SE, et al. An electronic cigarette pod system delivering 6-methyl nicotine, a synthetic nicotine analog, marketed in the United States as "PMTA exempt". medRxiv [Preprint]. 2023 Nov 22:2023.11.21.23298778. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)