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Cat. No.: HY-N21814

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Salbostatin

Salbostatin is a competitive Trehalase inhibitor, with an IC₅₀ of 8.3 μM against silkworm trehalase and a K_i of 180 nM against porcine trehalase. Salbostatin is isolated from Streptomyces albus. Salbostatin shows no antibacterial activity, and does not inhibit porcine intestinal mucosa sucrase (EC 3.2.1.26) or maltase (EC 3.2.1.20). Salbostatin can be used in studies related to the development of plant protectants.

For research use only. We do not sell to patients.

CAS No.: 128826-89-1
Formula: C₁₃H₂₃NO₈
Molecular Weight:321.32

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Please store the product under the recommended conditions in the Certificate of Analysis.

Salbostatin Chemical Structure

CAS No.: 128826-89-1

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
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Biological Activity

Description

IC₅₀ & Target

^[1]

Microbial Metabolite

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In Vitro

Salbostatin inhibits silkworm trehalase with an IC₅₀ of 8.3 μM^[1].
Salbostatin potently and competitively inhibits porcine kidney trehalase with a K_i = 180 nM, weakly inhibits murine liver aldose reductase, and does not inhibit porcine small intestine saccharase, maltase, or exhibit antibiotic activity^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 128826-89-1
Molecular Weight 321.32
Formula C₁₃H₂₃NO₈
SMILES

O[C@H]1[C@H](O)C(CO)=C[C@H](N[C@H]2CO[C@H](CO)[C@@H](O)[C@@H]2O)[C@@H]1O
Structure Classification
- Saccharides
- Polysaccharides
Initial Source
- Microorganisms
Streptomyces albus
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Yamagishi T, et al. Total synthesis of the trehalase inhibitor salbostatin[J]. Chemistry–A European Journal, 1995, 1(9): 634-636.

[2]. Vértesy L, et al. The trehalase inhibitor salbostatin, a novel metabolite from Streptomyces albus, ATCC21838[J]. Angewandte Chemie International Edition in English, 1994, 33(18): 1844-1846.

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Salbostatin

All Endogenous Metabolite Isoforms

Biological Activity

Description

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In Vitro

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Salbostatin Related Classifications

HY-N21814 Related Classifications

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