SARS-CoV-2-IN-77
SARS-CoV-2-IN-77 (compound 11e) is a cathepsin L and cathepsin S inhibitor with Ki values of 111 nM and 103 nM, respectively. SARS-CoV-2-IN-77 inhibits SARS-CoV-2 with an EC50 value of 38.4 nM in Calu-3 cells without showing cytotoxicity.
For research use only. We do not sell to patients.
- Formula: C23H25Cl2N3O3
- Molecular Weight:462.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Cathepsin Isoforms
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Biological Activity
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cathepsin L 111 nM (Ki) |
cathepsin S 103 nM (Ki) |
SARS-CoV-2 38.4 nM (EC50) |
Chemical Information
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Molecular Weight 462.37
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Formula C23H25Cl2N3O3
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SMILES
CC(C[C@@H](C(N[C@@H](CC1=CC=CC=C1)C#N)=O)NC(COC2=C(C=C(C=C2)Cl)Cl)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)