Sativanone
Sativanone is a compound that can be isolated from Dalbergia tonkinensis. Sativanone is a potent α-glucosidase inhibitor, with an EC50 of 0.357 mg/mL for rat α-glucosidase. Sativanone has antibacterial activity against Ralstonia solanacearum. Sativanone also has anti-senescent and antioxidant effects.
For research use only. We do not sell to patients.
- CAS No.: 70561-31-8
- Formula: C17H16O5
- Molecular Weight:300.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BV-2 | IC50 |
>50 μM
Compound: 23
|
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production
|
[PMID: 29482940] |
| RAW264.7 | IC50 |
>100 μM
Compound: 9
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
|
[PMID: 23743282] |
Chemical Information
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CAS No. 70561-31-8
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Molecular Weight 300.31
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Formula C17H16O5
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SMILES
O=C1[C@H](C2=C(C=C(C=C2)OC)OC)COC3=CC(O)=CC=C31
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)