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Cat. No.: HY-N7308

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Effususol A

Effususol A is a natural phenolic compound.

For research use only. We do not sell to patients.

CAS No.: 1869082-58-5
Formula: C₁₈H₂₀O₃
Molecular Weight:284.35

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Effususol A Chemical Structure

CAS No.: 1869082-58-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Effususol A is a natural phenolic compound.

IC₅₀ & Target

human OAT3

8.3 μM (IC₅₀)

human OAT1

43.1 μM (IC₅₀)

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	IC₅₀	43.1 μM Compound: 11, Racemic mixture	Inhibition of OAT1 (unknown origin) expressed in HEK293 cells assessed as reduction in 6-CF uptake measured after 5 mins by fluorescence assay Inhibition of OAT1 (unknown origin) expressed in HEK293 cells assessed as reduction in 6-CF uptake measured after 5 mins by fluorescence assay	[PMID: 30892891]
HEK293	IC₅₀	8.3 μM Compound: 11, Racemic mixture	Inhibition of OAT3 (unknown origin) expressed in HEK293 cells assessed as reduction in 6-CF uptake measured after 5 mins by fluorescence assay Inhibition of OAT3 (unknown origin) expressed in HEK293 cells assessed as reduction in 6-CF uptake measured after 5 mins by fluorescence assay	[PMID: 30892891]

In Vitro

Effususol A concentration-dependently inhibits the uptake of 6-carboxyfluorescein (6-CF) in HEK293 cells stably overexpressing OAT1 or OAT3, with IC₅₀ values of 43.1 μM and 8.3 μM, respectively, after a 5-minute co-incubation ^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1869082-58-5
Molecular Weight 284.35
Formula C₁₈H₂₀O₃
SMILES

OC(C(C)=C1CC2)=CC=C1C3=C2C=C(O)C=C3C(OC)C
Structure Classification
- Others
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Li X, et al. Dihydrophenanthrenes from Juncus effusus as Inhibitors of OAT1 and OAT3. J Nat Prod. 2019;82(4):832-839. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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