468 Results for "

O2

" in MedChemExpress (MCE) Product Catalog:
Products (468)

468 Results for "O2" in MCE Product Catalog:

Cat. No.: HY-204504
CAS No.: 159351-98-1
Target:  

Drug Derivative

Research Areas:  

Others

42-O-(2-Aminoethyl)-rapamycin (compound 2.3) is a derivative of the mTOR inhibitor rapamycin. 42-O-(2-Aminoethyl)-rapamycin can be used in pharmaceutical research for developing conjugates .
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Cat. No.: HY-177901
CAS No.: 159954-97-9
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

3'-O-(2-Nitrobenzyl)-dATP is a reversible and photolabile DNA synthesis terminator. 3'-O-(2-Nitrobenzyl)-dATP incorporates into growing DNA strands to terminate synthesis in a base-specific manner. 3'-O-(2-Nitrobenzyl)-dATP undergoes efficient photolytic removal of its 3'-protecting group upon UV exposure to enable reinitiation of DNA synthesis. 3'-O-(2-Nitrobenzyl)-dATP supports development of the Base Addition Sequencing Scheme (BASS) via a complete stop-start DNA synthesis cycle .
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Cat. No.: HY-N7092S21
Synonyms: D(-​)​-​Fructose-18O-2
D-Fructose- 18O-2 is the 18O labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants .
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Cat. No.: HY-W048496
CAS No.: 223777-16-0
Research Areas:  

Cancer

2'-O-(2-Methoxyethyl)-cytidine is a synthetic oligonucleotide derived from uridine. 2'-O-(2-Methoxyethyl)-cytidine has good hybridization properties and high stability, and can be used in the research of oligonucleotide chemotherapeutic agents .
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Cat. No.: HY-185273
CAS No.: 959755-49-8
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

3'-O-(2-Nitrobenzyl)-dGTP is a reversible terminator. 3'-O-(2-Nitrobenzyl)-dGTP can be recognized and incorporated by DNA polymerases, thereby temporarily terminating DNA primer extension; after the 2-nitrobenzyl blocking group is removed via laser irradiation, a free 3'-OH can be regenerated to allow subsequent polymerase-mediated extension. 3'-O-(2-Nitrobenzyl)-dGTP can be used in DNA sequencing studies .
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Cat. No.: HY-137683A
Synonyms: GDPβS trisodium
Target:  

Adenylate Cyclase

Research Areas:  

Cardiovascular Disease

Guanosine 5'-O-(2-thiodiphosphate) trisodium (GDPβS trisodium) is a non-hydrolyzable derivative of GDP. Guanosine 5'-O-(2-thiodiphosphate) trisodium acts as an inhibitor of adenylyl cyclase (AC) with a Ki value of 600 nM. In the absence of glutamic-pyruvic transaminase (GPT) in cerebral cortex membranes of rodent models, Guanosine 5'-O-(2-thiodiphosphate) trisodium partially activates AC with an EC50 of 400 nM. Guanosine 5'-O-(2-thiodiphosphate) trisodium prevents norepinephrine-induced nitric oxide release in ventricular myocytes [2] .
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Cat. No.: HY-P11545
CAS No.: 164028-89-1
Target:  

Drug Derivative

Research Areas:  

Inflammation/Immunology

2-[O-(2-Azidoethyl)-D-serine]-cyclosporin A (Compound 33) is a Cyclosporine derivative. 2-[O-(2-Azidoethyl)-D-serine]-cyclosporin A shows an IC50 of 0.11 μg/mL in the mixed lymphocyte reaction .
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Cat. No.: HY-N17258
CAS No.: 129235-39-8
Quercetin 3-O-(2G-β-D-xylopyranosylrutinoside) is an oviposition inhibitory factor. Quercetin 3-O-(2G-β-D-xylopyranosylrutinoside) can be isolated from the leaves of Orixa japonica. When presented together with the oviposition stimulant from Citrus unshiu (Satsuma mandarin), Quercetin 3-O-(2G-β-D-xylopyranosylrutinoside) inhibits oviposition by gravid female Papilio xuthus (Asian swallowtail) .
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Cat. No.: HY-180123
CAS No.: 159351-89-0
Target:  

Drug Intermediate

Research Areas:  

Infection

42-O-(2-Azidoethyl)-Rapamycin (Compound 4) is an azide compound that can be used as a drug intermediate to synthesize the derivative of Rapamycin (HY-10219) .
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Cat. No.: HY-403544
CAS No.: 2324147-95-5
Target:  

PROTAC Linkers

Research Areas:  

Others

CbzNH-(C5-O)2-C4-Boc is a PROTAC linker. CbzNH-(C5-O)2-C4-Boc can be used for the synthesis of PROTAC CRBN-6-5-5-VHL (HY-136262) .
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Cat. No.: HY-137683B
CAS No.: 97952-36-8
Synonyms: GDPβS trilithium
Target:  

Others

Research Areas:  

Others

Guanosine 5'-O-(2-thiodiphosphate) (trilithium) is a guanosine nucleotide that is a stable free radical .
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Cat. No.: HY-174866
CAS No.: 3055107-34-8
Research Areas:  

Cancer

BT-O2C is a p300 PROTAC degrader. BT-O2C induces p300 degradation via proteasome- and ubiquitin-like modification-dependent pathways, downregulates the expression of CIC::DUX4 sarcoma target genes, and exerts cytotoxicity against such sarcoma cells. BT-O2C can be used in CIC::DUX4 sarcoma-related studies .
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Cat. No.: HY-D3000
NIR-RED ROS-H2O2 Probe is a near-infrared fluorescent probe used for detecting hydrogen peroxide (H₂O₂) and featuring dual-modal fluorescence/photoacoustic imaging capabilities. NIR-RED ROS-H2O2 Probe successfully detects the upregulated fluorescence signal of H₂O₂ in HepG2 cells and a mouse liver injury model. NIR-RED ROS-H2O2 Probe can be used as a biomarker detection tool for drug-induced liver injury (DILI) .
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Cat. No.: HY-152868
Research Areas:  

Others

3’-O-(2-Azidoethyl)adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-O-(2-Azidoethyl)adenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Cat. No.: HY-152870
CAS No.: 2226475-42-7
Research Areas:  

Others

2’-O-(2-Azidoethyl)adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2’-O-(2-Azidoethyl)adenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Cat. No.: HY-152382
CAS No.: 2305415-84-1
Research Areas:  

Cancer

3’-O-(2-Methoxyethyl)cytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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Cat. No.: HY-154285
CAS No.: 870599-31-8
Research Areas:  

Cancer

3’-O-(2-Methoxyethyl) uridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
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Cat. No.: HY-128930
CAS No.: 881895-59-6
Target:  

ADC Linkers

Research Areas:  

Cancer

6-O-2-Propyn-1-yl-D-galactose is a nonclaevable glycolinker for the functionalization of cytotoxic agents and applications in antibody-agent conjugation. 6-O-2-Propyn-1-yl-D-galactose is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-23789
CAS No.: 473278-54-5
Synonyms: 2'-O-MOE-rG
2′-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG) is a 2'-O-methoxyethyl-modified nucleoside analogue and an important intermediate in the synthesis of nucleic acid drugs. 2′-O-(2-Methoxyethyl)guanosine neither effectively phosphorylated by cytosolic nucleoside kinases, nor are they incorporated into cellular DNA or RNA [2].
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