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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
226 Results for "
uv
" in MedChemExpress (MCE) Product Catalog:
Products (226)
226 Results for "uv" in MCE Product Catalog:
Cat. No.: HY-103300
CAS No.: 1186195-63-0
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NPE-caged-proton is a reagent that releases protons under UV light and has the activity of activating the fusion protein GP64 under weak acidic conditions. NPE-caged-proton can promote the binding of enveloped viruses to liposome membranes with acidic phospholipids in an environment of pH 4.0 to 5.5, thereby initiating membrane fusion. The ultraviolet unblocking effect of NPE-caged-proton can lower the environmental pH, thereby triggering the process of viral membrane fusion. When studying the interaction between viruses and cell membranes, NPE-caged-proton provides a valuable tool for revealing the subtle behaviors of viruses in different chemical and biochemical environments .
Cat. No.: HY-17587R
CAS No.: 36861-47-9
Synonyms: 4-MBC (Standard); Enzacamene (Standard)
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4-Methylbenzylidene camphor (Standard) is the analytical standard of 4-Methylbenzylidene camphor. This product is intended for research and analytical applications. 4-Methylbenzylidene camphor (4-MBC) is an endocrine disrupter that produces estrogen-like effects. 4-Methylbenzylidene camphor decreases the proliferation of human trophoblast cells and induces apoptosis. 4-Methylbenzylidene camphor activates PI3K/AKT and ERK1/2 signaling pathways and elevates intracellular ROS production. 4-Methylbenzylidene camphor is a ultraviolet (UV) filter and may hamper normal placental formation during early pregnancy .
Cat. No.: HY-W016352
CAS No.: 96-97-9
Synonyms: Anilotic acid, 99%
Research Areas:
2-Hydroxy-5-nitrobenzoic acid, 99% (Anilotic acid, 99%) is a basic chemical raw material and organic synthesis intermediate that can be used to synthesize Mesalamine (HY-15027). 2-Hydroxy-5-nitrobenzoic acid, 99% is a matrix for ultraviolet matrix-assisted laser desorption/ionization (UV-MALDI) mass spectrometry. 2-Hydroxy-5-nitrobenzoic acid, 99% can also serve as an HPLC analytical standard, pH indicator, and heavy metal detection agent. 2-Hydroxy-5-nitrobenzoic acid, 99% can also be used to study the oxidation of phenolic compounds .
Cat. No.: HY-164159
CAS No.: 130603-71-3
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α-Glucosylrutin, a flavonoid, is a potent antioxidant with free radical scavenging activity. α-Glucosylrutin reduces MMP-1 gene expression, protein expression, and enzyme activity, and reduces MMP-2 protein expression and enzyme activity in UVA-irradiated human dermal fibroblasts. α-Glucosylrutin prevents oxidative stress-induced intracellular tyrosine residue phosphorylation and counteracts intracellular thiol level depletion in human skin cells. α-Glucosylrutin is effective in the prevention of dermatologic diseases in which oxidative stress is of pathogenetic relevance, e.g. in polymorphous light eruption (PLE). α-Glucosylrutin can be used for the research of UV-induced skin photodamage/photoaging .
Cat. No.: HY-N5072R
CAS No.: 17817-31-1
Synonyms: 4',6,7-Trihydroxyisoflavone (Standard)
Category:
Flavonoids Glycine max (L.) merr Phenols Polyphenols Leguminosae Extract Plants Isoflavones
Target:
Cat. No.: HY-W075183
CAS No.: 31274-51-8
Synonyms: Tris-biphenyl triazine
2,4,6-Tri([1,1'-biphenyl]-4-yl)-1,3,5-triazine (Tris-biphenyl triazine) is a nitrogen-containing MOF ligand. 2,4,6-Tri([1,1'-biphenyl]-4-yl)-1,3,5-triazine can be used in electronic materials and organic light-emitting diodes (OLEDs). Additionally, 2,4,6-Tri([1,1'-biphenyl]-4-yl)-1,3,5-triazine serves as a highly efficient, broad-spectrum UV absorber.
Cat. No.: HY-W093282
CAS No.: 8013-07-8
Synonyms: Soybean oil epoxide
Cat. No.: HY-113621B
CAS No.: 2757574-06-2
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Ageladine A dihydrochloride is an inhibitor of matrix metalloproteinase (MMP) isolated from the marine sponge Agelas nakamurai, possessing anti-angiogenic activity. Ageladine A dihydrochloride not only inhibits MMP-2 but also MMP-1, MMP-8, MMP-9, MMP-12, and MMP-13, with IC50 values of 4.65 μM, 2.79 μM, 907.12 nM, 1.83 μM, 767.57 nM, and 1.09 μM, respectively. Additionally, Ageladine A dihydrochloride is a pH-sensitive membrane-permeable dye that emits fluorescence in the blue-green range upon UV excitation, featuring a maximum absorption peak at 370 nm. Furthermore, Ageladine A dihydrochloride serves as a reliable and stable fluorescent pH sensor for detecting changes in intracellular pH values .
Cat. No.: HY-180985
Azo-PROTAC-4C-cis is a BCR-ABL PROTAC degrader, and its degradation efficiency of BCR-ABL is much lower than that of its trans isomer Azo-PROTAC-4C-trans (HY-180983). Azo-PROTAC-4C-cis is the product of the conformational transformation of Azo-PROTAC-4C-trans under ultraviolet (UV) light irradiation. Azo-PROTAC-4C-cis can be converted into highly active Azo-PROTAC-4C-trans under visible light, thereby initiating protein degradation. Azo-PROTAC-4C-cis can be used for the study of myeloid leukemia .
Cat. No.: HY-189150
CAS No.: 1643925-08-9
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NSP-116 is an orally active antioxidant and neuroprotective agent. NSP-116 protects corneal epithelial cells from UV-A and blue light LED-induced photo-oxidative damage. NSP-116 scavenges DPPH, superoxide anion, and hydroxyl radicals, inhibits light-induced ROS production in photoreceptor cells, and inhibits lipid peroxidation in retinal homogenates. NSP-116 prevents light-induced photoreceptor cell death and retinal degeneration, and inhibits intracellular Fe 2+ accumulation, autophagy, apoptosis, p38 phosphorylation, and microglial/macrophage activation. NSP-116 exerts neuroprotective effects in hemorrhagic stroke models. NSP-116 can be used for research on photokeratitis, dry age-related macular degeneration, and intracranial hemorrhage .
Cat. No.: HY-B1234S
Cat. No.: HY-W583212
CAS No.: 14354-67-7
Synonyms: ZnMP
Cat. No.: HY-W713284
CAS No.: 2734919-82-3
Synonyms: (E)-Octyl methoxycinnamate-d3
Target:
Isotope-Labeled Compounds Cytochrome P450 Estrogen Receptor/ERR Androgen Receptor Thyroid Hormone Receptor
Research Areas:
Octinoxate-d3 is the deuterium labeled Octinoxate (HY-B1234). Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo .
Cat. No.: HY-W750212
CAS No.: 2734676-29-8
Synonyms: Orange II-13C6; D&C Orange NO. 4-13C6
Cat. No.: HY-DY1097
CAS No.: 107091-89-4
Solvent and concentration: DMSO: 10 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
Cat. No.: HY-DY2041
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Callose Staining Solution (Aniline Blue, Bright-Field Method) is a fluorescent dye used for detecting callose in plant tissues, green algal cell walls, plant cells, and protoplasts. Callose Staining Solution (Aniline Blue, Bright-Field Method) specifically binds to callose, a β-(1,3)-D-glucan polymer, and exhibits blue-green fluorescence under alkaline conditions with reduced background staining and non-toxicity to living cells. Callose Staining Solution (Aniline Blue, Bright-Field Method) is suitable for observation under UV or epifluorescence microscopy (Ex/Em = 365-370/397-509 nm). Callose Staining Solution (Aniline Blue, Bright-Field Method) can be used in studies related to the visualization of callose deposition in plants .
Cat. No.: HY-W130288
CAS No.: 57536-86-4
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1-(1-Naphthyl)piperazine is a 5-HT receptor modulator that acts as both a 5-HT2A receptor antagonist and 5-HT1A receptor agonist, and binds to human 5-HT6 receptor with a Ki of 120 nM. 1-(1-Naphthyl)piperazine partially inhibits forskolin-stimulated adenylate cyclase activity in calf substantia nigra. 1-(1-Naphthyl)piperazine inhibits UV-induced immunosuppression. 1-(1-Naphthyl)piperazine induces S-phase cell cycle delay, apoptosis and increases ROS levels, leading to inhibit MNT-1 cell proliferation. 1-(1-Naphthyl)piperazine can be used for melanoma research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
