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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2954 Results for "
D3
" in MedChemExpress (MCE) Product Catalog:
Products (2954)
2954 Results for "D3" in MCE Product Catalog:
Cat. No.: HY-W701842
CAS No.: 2489623-84-7
Synonyms: 1-Oleoyl-3-chloropropanediol-d5
Cat. No.: HY-11056
CAS No.: 1010382-72-5
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Research Areas:
PF-04363467 is a highly preferring D3R antagonist. PF-04363467 produces dose-dependent changes in the EEG profile of freely moving rats. PF-4363467 attenuates opioid drug-seeking behavior without concomitant D2 side effects. PF-04363467 can be used for the study of addiction, cognitive and mental illness .
Cat. No.: HY-152685
Target:
Research Areas:
4-Amino-1-(β-D-ribofurano syl)-7H-pyrrolo [2.3-d] pyrimidine-5-carboxamide is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
Cat. No.: HY-W701859
CAS No.: 2489621-82-9
Synonyms: 1-Oleoyl-2-Stearoyl-3-chloropropanediol-d5
Cat. No.: HY-122849
CHMFL-KIT-031 is a highly selective KIT V559D inhibitor, with an IC50 of 28 nM. CHMFL-KIT-031 potently affects KIT V559D mutant’s phosphorylation at Y703/719/823 sites. CHMFL-KIT-031 inhibits the tumor growth in BaF3-TEL-KIT-V559D cell inoculated mouse model .
Cat. No.: HY-D0303AS
CAS No.: 1450729-16-4
Synonyms: Solvent Orange 3-d5 hydrochloride
Cat. No.: HY-179407
CAS No.: 2574572-03-3
Target:
Research Areas:
LT-104A is a potent PDE4 inhibitor that elevates intracellular cAMP levels (EC50 = 1.9 μM) and inhibits PDE4D3 activity (IC50 = 9.3 μM). LT-104A activates the cAMP-PKA-CREB anti-inflammatory signaling pathway and suppresses NF-κB-related gene expression (Il1b and Nos2). LT-104A can be used for inflammation-related disease research .
Cat. No.: HY-187538
Target:
Research Areas:
DR/5-HT7AR Ligand-1 is a ligand with a Ki value of 1.24 nM against human D2R, 5.78 nM against human D3R, 0.67 nM against human 5-HT1AR, and 19.9 nM against human 5-HT7AR. DR/5-HT7AR Ligand-1 can be used for the research of schizophrenia .
Cat. No.: HY-P73672
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RYK; JTK5A Protein Tyrosine Kinase; Prev. JTK5A; RYK Receptor-Like Tyrosine Kinase; D3S3195; Receptor Protein-Tyrosine Kinase; JTK5; Hydroxyaryl-Protein Kinase; RYK1; Receptor Like Tyrosine Kinase; Tyrosine-Protein Kinase RYK
Species:
Human
Source:
HEK293
Cat. No.: HY-119799
CAS No.: 582332-31-8
Target:
Research Areas:
UK-500001 is an orally active inhibitor for phosphodiesterase 4 (PDE4), which inhibits PDE4D3 (IC50 is 0.28 nM), PDE4B2 (IC50 is 22.8 nM), PDE4A4 (IC50 is 26.1 nM) and PDE4C2 (IC50 is 271 nM). UK-500001 exhibits anti-inflammatory efficacy and inhibits TNF-α and IFN-γ release in human and rodent macrophagic cell lines in nanomolar levels. UK-500001 ameliorates chronic obstructive pulmonary disease (COPD) and asthma .
Cat. No.: HY-N0753
CAS No.: 877822-41-8
Cat. No.: HY-P87288
Synonyms: 3 PGDH antibody; 3-PGDH antibody; 3-phosphoglycerate dehydrogenase antibody; 3PGDH antibody; D-3-phosphoglycerate dehydrogenase antibody; EC 1.1.1.95 antibody; Epididymis secretory protein Li 113 antibody; HEL S 113 antibody; NLS antibody; NLS1 antibody
Cat. No.: HY-123828
CAS No.: 389080-71-1
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MLS6585 is a selective D1 dopamine receptor (D1R) positive allosteric modulator that enhances Dopamine (HY-B0451)-stimulated G protein/β-arrestin signaling and affinity without intrinsic D1R agonist activity. MLS6585 is inactive at D2R, D3R, D4R, and β2-adrenergic receptors. MLS6585 partially restores signaling of loss-of-function DRD1 variants and enhances responses to multiple agonists [3] .
Cat. No.: HY-181049
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Research Areas:
FMJ-01-054 is a selective dopamine D4 Receptor (D4R) antagonist with a Ki od 77.7 nM. FMJ-01-054 shows subtype selectivity over D2R and D3R. FMJ-01-054 inhibits D4R-mediated β-arrestin recruitment and cAMP production with IC50 values of 3800 nM and 134 nM, respectively. FMJ-01-054 has desirable plasma half-life and brain exposure in rats. FMJ-01-054 can be used for the research of neurological disorders .
Cat. No.: HY-N20741
CAS No.: 615275-47-3
Target:
Cat. No.: HY-W044285
CAS No.: 324017-22-3
Target:
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
