Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
349 Results for "
cap
" in MedChemExpress (MCE) Product Catalog:
Products (349)
349 Results for "cap" in MCE Product Catalog:
Cat. No.: HY-P85727
Synonyms: CASP8; MCH5; Caspase-8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; cap4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH
Cat. No.: HY-P86141
Synonyms: CASP8; MCH5; Caspase-8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; cap4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH
Synonyms: N-Behenoyl-D-erythro-sphingosine; C22-Ceramide; Cer d18:1/22:0
Target:
Research Areas:
C22-Ceramide (d18:1/22:0) (N-Behenoyl-D-erythro-sphingosine) is an ultra-long-chain ceramide containing a C22:0 behenoyl acyl chain. C22-Ceramide can be glycosylated via CGT-3 to form C22 glucosylceramide (C22 GlcCer), which in turn maintains clathrin membrane localization and lysosomal homeostasis, inhibits TOR signaling and promotes SKN-1 activation, thereby enhancing oxidative stress resistance and extending the lifespan of C. elegans. C22-Ceramide can be used in research on cardiometabolic diseases such as type 2 diabetes, obesity, dyslipidemia, coronary artery disease and thin-cap fibroatheroma (TCFA), as well as oxidative stress and aging-related studies .
Cat. No.: HY-184264
CAS No.: 1309199-94-7
CHVB-066 is an alphavirus non-structural protein nsP1 inhibitor that exhibits varying degrees of inhibitory activity against nsP1 of CHIKV and VEEV. CHVB-066 inhibits MTase and GTase activities and disrupts the capping process of viral RNA, including inhibiting CHIKV replication, reducing progeny viruses, and preventing cytopathic effects. It shows varying degrees of inhibitory activity against nsP1 of CHIKV and VEEV but lacks anti-SFV replication activity, displays cross-resistance with MADTP series compounds, and requires nsP2/nsP3 mutations to develop complete drug resistance. This inhibitor with varying inhibitory activity against nsP1 of CHIKV and VEEV can be widely applied to relevant studies on chikungunya virus infection and chikungunya fever .
Cat. No.: HY-P12350
CAS No.: 1261043-80-4
Target:
Research Areas:
Ac-I3K-NH2 is a surfactant-like peptide. Ac-I3K-NH2 self-assembles into β-sheet nanofibers through β-sheet hydrogen bonding, hydrophobic interactions, and electrostatic repulsion. Ac-I3K-NH2 forms ribbon-like nanofibers with nanoscale widths, adopting a β-sheet conformation, with lateral stacking driven by isoleucine side-chain contacts. Ac-I3K-NH2 templates the sol-gel condensation of tetraethoxysilane, producing silica nanotubes. Ac-I3K-NH2 templates the synthesis of one-dimensional Pt nanostructures with P7A as a capping agent .
Cat. No.: HY-P80773A
Synonyms: CDKN1A; cap20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21
Cat. No.: HY-W996116
CAS No.: 1933460-23-1
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
AZM198 is an orally active myeloperoxidase (MPO) inhibitor. AZM198 irreversibly inactivates MPO (IC50=0.015 μM) via covalent binding to the heme prosthetic group, preferentially targets extracellular MPO activity, and reduces neutrophil extracellular trap formation, reactive oxygen species production and degranulation. AZM198 increases the fibrous cap thickness of atherosclerotic plaques, reduces lesion area, ameliorates hepatic steatosis and fibrosis in non-alcoholic steatohepatitis, and alleviates proteinuria and inflammatory infiltration associated with glomerulonephritis. AZM198 also decreases circulating levels of high-sensitivity Cardiac Troponin I and IL-1β, and mitigates endothelial cell injury. Therefore, AZM198 is suitable for research on various MPO-related diseases, including atherosclerotic cardiovascular disease, myocardial infarction, ischemic stroke, non-alcoholic steatohepatitis and crescentic glomerulonephritis .
Cat. No.: HY-P703190
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: CLIP1; cap-Gly Domain-Containing Linker Protein 1; Prev. RSN; Cytoplasmic Linker Protein 1; CLIP-170; Restin; CYLN1; Reed-Sternberg Intermediate Filament-Associated Protein; CLIP170; Cytoplasmic Linker Protein CLIP-170; CLIP; CLIP1 Protein; Restin (Reed-S
Species:
Human
Source:
E. coli
Cat. No.: HY-P74525
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: TGFBI; RGD-Containing Collagen-Associated Protein; Prev. CSD1; Beta Ig-H3; Prev. CSD2; RGD-cap; Prev. CSD3; Transforming Growth Factor, Beta-Induced, 68kDa; Prev. LCD1; Transforming Growth Factor Beta-Induced 68kDa; BIGH3; Transforming Growth Factor Beta
Species:
Human
Source:
HEK293
Cat. No.: HY-P702961
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CTNNA1; Catenin (Cadherin-Associated Protein), Alpha 1, 102kDa; Catenin Alpha 1; Epididymis Secretory Sperm Binding Protein; Catenin Alpha-1; Cadherin-Associated Protein; cap102; Alpha E-Catenin; Renal Carcinoma Antigen NY-REN-13; CTNNA1 Protein; Alpha-E-
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P80624A
Synonyms: CASP8; MCH5; Caspase-8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; cap4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH
Cat. No.: HY-P70152
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: EIF4E; EIF-4F 25 KDa Subunit; Prev. EIF4EL1; Eukaryotic Translation Initiation Factor 4E-Like 1; Prev. EIF4F; AUTS19; EIF4E1; CBP; MRNA cap-Binding Protein; Eukaryotic Translation Initiation Factor 4E; EIF-4E
Species:
Human
Source:
E. coli
Cat. No.: HY-P70886
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NDRG1; Protein NDRG1; Prev. cap43; Protein Regulated By Oxygen-1; DRG1; PROXY1; RTP; CMT4D; TDD5; HMSNL; NDR1; RIT42; Reducing Agents And Tunicamycin-Responsive Protein; TARG1; N-Myc Downstream-Regulated Gene 1 Protein; Rit42; Nickel-Specific Induction Pr
Species:
Human
Source:
E. coli
Cat. No.: HY-P71708
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CASP8; Apoptotic Cysteine Protease; Caspase 8; Apoptotic Protease Mch-5; FLICE; FADD-Like ICE; MCH5; cap4; MACH; FADD-Homologous ICE/CED-3-Like Protease; Caspase-8; FADD-Homologous ICE/Ced-3-Like Protease; Casp-8; MACH-Beta-1/2/3/4 Protein; Caspase 8, Apo
Species:
Human
Source:
E. coli
Cat. No.: HY-P700570
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDKN1A; Cdk-Interacting Protein 1; Prev. CDKN1; MDA-6; cap20; Melanoma Differentiation Associated Protein 6; CIP1; Melanoma Differentiation-Associated Protein 6; WAF1; Wild-Type P53-Activated Fragment 1; SDI1; CDK-Interaction Protein 1; P21; CDK-Interacti
Species:
Human
Source:
E. coli
Cat. No.: HY-P703422
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: EIF4E; EIF-4F 25 KDa Subunit; Prev. EIF4EL1; Eukaryotic Translation Initiation Factor 4E-Like 1; Prev. EIF4F; AUTS19; EIF4E1; CBP; MRNA cap-Binding Protein; Eukaryotic Translation Initiation Factor 4E; EIF-4E
Species:
Human
Source:
E. coli
Cat. No.: HY-P790103
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TRAF3; CD40 Receptor-Associated Factor 1; TNF Receptor Associated Factor 3; TNF Receptor-Associated Factor; CRAF1; CD40 Associated Protein 1; cap-1; CD40 Binding Protein; LAP1; CD40-Binding Protein; RNF118; IMD132B; CD40bp; IMD132A; RING-Type E3 Ubiquitin
Species:
Human
Source:
Sf9 insect cells
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
