59 Results for "

L-dopa

" in MedChemExpress (MCE) Product Catalog:
Products (59)

59 Results for "L-dopa" in MCE Product Catalog:

Cat. No.: HY-W037976
CAS No.: 25369-78-2
Synonyms: 5-Chloro-2-mercaptobenzimidazole
Research Areas:  

Cancer

Tyrosinase-IN-22 (compound 4) is an inhibitor of tyrosinase substrates (L-tyrosine and L-dopa) with IC50s of 60 nM and 30 nM, respectively. Tyrosinase-IN-22 also shows potent antioxidant and anti-melanogenic properties, thus can be used for relevant researches .
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Cat. No.: HY-W152604
CAS No.: 5845-67-0
Synonyms: Cyclo(leu-gly)
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

Cyclo(glycyl-L-leucyl) (Cyclo(leu-gly)), a neuropeptide, down-regulates dopamine (DA) receptors and attenuates dopaminergic supersensitivity. Cyclo(glycyl-L-leucyl) inhibits the development of Morphine induced pain relief as well as dopamine receptor supersensitivity in rats. Cyclo(glycyl-L-leucyl) has the potential for the prevention of tardive and/or L-DOPA (HY-N0304)-induced dyskinesias .
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Cat. No.: HY-N0304S1
CAS No.: 201417-12-1
Synonyms: Levodopa-13C6; 3,4-Dihydroxyphenylalanine-13C6
L-DOPA- 13C6 is the 13C-labled L-DOPA . L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease .
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Cat. No.: HY-W012264
CAS No.: 200630-46-2
Synonyms: 3-Methoxy-L-tyrosine monohydrate; 3-O-Methyl-L-dopa monohydrate
Target:  

COMT

Research Areas:  

Neurological Disease

3-O-Methyldopa monohydrate (3-Methoxy-L-tyrosine monohydrate) is a significant metabolite of L-DOPA produced through the action of catechol O-methyltransferase (COMT). Unlike its precursor, 3-O-Methyldopa does not serve as a substrate or inhibitor of L-amino acid decarboxylase activity. Additionally, the inhibition of COMT can amplify the anti-Parkinson effects of L-DOPA.
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Cat. No.: HY-113468AR
CAS No.: 300-48-1
Synonyms: 3-Methoxy-L-tyrosine (Standard); 3-O-Methyl-L-dopa (Standard)
3-O-Methyldopa (Standard) is the analytical standard of 3-O-Methyldopa. This product is intended for research and analytical applications. 3-O-Methyldopa (3-Methoxy-L-tyrosine) is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of l-DOPA and dopamine .
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Cat. No.: HY-116750
CAS No.: 4324-55-4
6-Hydroxykaempferol, a flavonoid, is a competitive tyrosinase inhibitor with an IC50 value of 124 μM. 6-Hydroxykaempferol has a Ki value of 148 μM relative to L-DOPA as a substrate and effectively inhibits the activity of the enzyme by binding to the active site of the enzyme .
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Cat. No.: HY-P2825
CAS No.: 9002-09-9
Synonyms: TDC; TyrDC
Target:  

Endogenous Metabolite

Research Areas:  

Others

Tyrosine decarboxylase, Microorganism (TDC) is a tyrosine decarboxylase produced by microorganisms. Tyrosine decarboxylase is a PLP-dependent enzyme that catalyzes the decarboxylation of L-tyrosine, L-phenylalanine, and L-dopa to produce tyramine, 2-phenethylamine, and dopamine, respectively. Tyrosine decarboxylase mediates acid stress resistance, maintains intracellular pH homeostasis, and generates proton motive force .
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Cat. No.: HY-B0404AR
CAS No.: 14919-77-8
Synonyms: Ro 4-4602 hydrochloride (Standard)
Benserazide hydrochloride (Standard) (Serazide (Standard)) is the analytical standard of Benserazide hydrochloride (HY-B0404A). This product is intended for research and analytical applications. Benserazide hydrochloride (Serazide) is an aromatic L-amino acid decarboxylase (AADC) and L-DOPA decarboxylase inhibitor. Benserazide hydrochloride is also a PKM2 inhibitor. Benserazide hydrochloride directly binds to and blocks PKM2 enzyme activity, leading to inhibition of aerobic glycolysis concurrent up-regulation of OXPHOS. Benserazide hydrochloride can be used for the study of Parkinson's disease and melanoma .
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Cat. No.: HY-149207
CAS No.: 240797-64-2
Purity:  98.12%
Target:  

Tyrosinase

Research Areas:  

Metabolic Disease

Tyrosinase-IN-11 is a potent tyrosinase inhibitor with IC50s of 50 nM and 64 nM for L-tyrosinase and L-dopa, respectively. Tyrosinase-IN-11 has significant antioxidant activity and low cytotoxicity. Tyrosinase-IN-11 has the potential for skin hyperpigmentation research .
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Cat. No.: HY-B0404AS
Synonyms: Ro 4-4602-d3 hydrochloride
Benserazide-d3 (hydrochloride) is the deuterium labeled Benserazide hydrochloride (HY-B0404A). Benserazide hydrochloride (Serazide) is an aromatic L-amino acid decarboxylase (AADC) and L-DOPA decarboxylase inhibitor. Benserazide hydrochloride is also a PKM2 inhibitor. Benserazide hydrochloride directly binds to and blocks PKM2 enzyme activity, leading to inhibition of aerobic glycolysis concurrent up-regulation of OXPHOS. Benserazide hydrochloride can be used for the study of Parkinson's disease and melanoma .
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Cat. No.: HY-116016AR
CAS No.: 39740-30-2
Synonyms: L-dopa ethyl ester hydrochloride (Standard); Levodopa ethyl ester hydrochloride (Standard)
Etilevodopa (hydrochloride) (Standard) is the analytical standard of Etilevodopa (hydrochloride). This product is intended for research and analytical applications. Etilevodopa (L-Dopa ethyl ester) hydrochloride, an ethyl-ester proagent of Levodopa, is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract. Etilevodopa hydrochloride is used for the treatment of Parkinson disease (PD). Levodopa is the direct precursor of dopamine and is a suitable proagent as it facilitates CNS penetration and delivers dopamine[1][2][3].
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Cat. No.: HY-113357R
CAS No.: 588-30-7
m-Coumaric acid (Standard) is the analytical standard of m-Coumaric acid. This product is intended for research and analytical applications. m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant. m-Coumaric acid is a BBB-penetrant metabolite of chlorogenic acid. m-Coumaric acid stimulates the cerebral nerves in vitro. m-Coumaric acid can evoke neurite outgrowth in hippocampal neuronal cells. m-Coumaric acid can promote neuronal differentiation. m-Coumaric acid increases spontaneous locomotor activity in mice by acting on the central nervous system. m-Coumaric acid inhibits the oxidation of L-dopa by epidermis tyrosinase. m-Coumaric acid attenuates non-catalytic protein glycosylation in retinas of diabetic rats .
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Cat. No.: HY-116016R
CAS No.: 37178-37-3
Synonyms: L-dopa ethyl ester (Standard); Levodopa ethyl ester (Standard)
Chlorbenside (Standard) is the analytical standard of Chlorbenside. This product is intended for research and analytical applications. Chlorbenside is an organochlorine pesticide. Chlorbenside targets organism such as mites and ticks and possesses efficient ovicidal and larvicidal activities .
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Cat. No.: HY-176895
CAS No.: 2377146-66-0
Target:  

Others

Research Areas:  

Cardiovascular Disease

L-Dopa precursor-1 (Compound 5a) is the precursor of 18F-L-Dopa. L-Dopa precursor-1 serves as a core basis for radioactive labeling precursors, allowing the introduction of non-metallic radioactive elements through radiolabeling reactions. L-Dopa precursor-1 can be used for the study of RDN surgery for refractory hypertension, chronic kidney disease .
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Cat. No.: HY-W401531S
CAS No.: 1259947-39-1
(R)-3-O-Methyldopa-d3 is a deuterium labeled (R)-3-O-Methyldopa, and (R)-3-O-Methyldopa is an R-enantiomer of 3-O-Methyldopa. 3-O-Methyldopa is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of L-DOPA and dopamine .
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Cat. No.: HY-W401531S1
CAS No.: 2714485-35-3
(R)-3-O-Methyldopa-d3 (hydrochloride) is a deuterium labeled (R)-3-O-Methyldopa, and (R)-3-O-Methyldopa is an R-enantiomer of 3-O-Methyldopa. 3-O-Methyldopa is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of L-DOPA and dopamine .
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Cat. No.: HY-N3237
CAS No.: 89199-99-5
Mulberrofuran H is a 2-arylbenzofuran derivative from the cultivated mulberry tree (Morus lhou (ser.) Koidz.). Mulberrofuran H demonstrates potent inhibition against substrates L-tyrosine (IC50=4.45 µM) and L-DOPA (IC50=19.70 µM). Mulberrofuran H also shows potent anti-inflammatory and antioxidative activities .
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Cat. No.: HY-175001
Research Areas:  

Neurological Disease

D1/D5 Receptor agonist-1 is a highly brain-penetrant and orally active D1/D5 receptor agonist. D1/D5 Receptor agonist-1 maintains considerable efficacy in the cAMP pathway and in β-arrestin recruitment, with EC50s of 3.7 nM (D1R cAMP), 91 nM (D1R β-arrestin), 129 nM (D1R internalization) and a Ki of 111 nM (D1R binding affinity). D1/D5 Receptor agonist-1 inhibits β-arrestin signaling in a rat with L-DOPA (HY-N0304) induced dyskinesias. D1/D5 Receptor agonist-1 can be used for the study of Parkinson’s disease .
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Cat. No.: HY-113468AS1
Synonyms: 3-Methoxy-L-tyrosine-d3 hydrate; 3-O-Methyl-L-dopa-d3 hydrate
3-O-Methyldopa-d3 (hydrate) is the deuterium labeled 3-O-Methyldopa. 3-O-Methyldopa (3-Methoxy-L-tyrosine) hydrate is a metabolite of L-DOPA (HY-N0304) that can cross the blood-brain barrier (BBB). 3-O-Methyldopa hydrate inhibits the astrocyte-mediated protective effect of L-DOPA (HY-N0304) on dopaminergic neurons. In addition, 3-O-Methyldopa hydrate has certain antidepressant and neuroprotective activities. 3-O-Methyldopa hydrate can be used in the research of nervous system diseases such as depression and Parkinson's disease .
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Cat. No.: HY-121939
CAS No.: 27244-64-0
Purity:  ≥95.0%
Research Areas:  

Others

6-Hydroxy-L-DOPA is a nucleic acid functionalized with electron-donating units .
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