121 Results for "

NGF

" in MedChemExpress (MCE) Product Catalog:
Products (121)

121 Results for "NGF" in MCE Product Catalog:

Cat. No.: HY-P99677
CAS No.: 2447755-72-6
Synonyms: ZTS-00075623
Izenivetmab (ZTS-00075623) is an anti-NGFB IgG2κ monoclonal antibody. Izenivetmab shows anti-inflammatory and analgesic effects by targeting anti-nerve growth factor (NGF). Izenivetmab can be used for the research of osteoarthritis .
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Cat. No.: HY-P99627
CAS No.: 1708936-80-4
Synonyms: NV-02; PG110; ABT-110

Target:  

Trk Receptor

Research Areas:  

Inflammation/Immunology

Frunevetmab (NV-02) is a felinized anti-nerve growth factor (NGF) monoclonal antibody with a Kd of 20 pM. Frunevetmab can effectively decrease osteoarthritis (OA) pain in cats .
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Cat. No.: HY-P99195
CAS No.: 1190239-42-9
Synonyms: REGN-475; SAR-164877

Target:  

Trk Receptor

Research Areas:  

Inflammation/Immunology

Fasinumab (Anti-Human NGF) is a human IgG4 monoclonal antibody to nerve growth factor (NGF). Fasinumab can be used in acute sciatica and knee osteoarthritis (OA) studies .
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Cat. No.: HY-N0380
CAS No.: 23720-80-1
Nardosinone, isolated from Nardostachys chinensis, is the first enhancer of the neuritogenic action of dbcAMP and staurosporine. Nardosinone may become a useful pharmacological tool for studying the mechanism of action of not only nerve growth factor (NGF) but also both the neuritogenic substances .
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Cat. No.: HY-117517
CAS No.: 141731-76-2
NG-012, potentiator of nerve growth factor (NGF), were isolated from the culture broth of Penicillium verruculosum F-4542. NG-012 potentiates the neurite outgrowth induced by NGF in rat pheochromocytoma cell line (PC12) .
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Cat. No.: HY-NP144
CAS No.: 93928-24-6
Nerve Growth Factor 7S,murine submaxillary gland is a high-molecular-weight α2β2γ2 neurotrophic factor complex isolated from murine submaxillary glands. Nerve Growth Factor 7S,murine submaxillary gland prevents the binding of active β-NGF dimers to neuronal receptors by sequestering the receptor-interacting region of β-NGF within the complex. Nerve Growth Factor 7S,murine submaxillary gland lacks neurotrophic activity due to the sequestration of β-NGF dimers and the occlusion of receptor-binding sites. Nerve Growth Factor 7S,murine submaxillary gland can be used in research related to neurodegenerative diseases .
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Cat. No.: HY-N12566
CAS No.: 156101-10-9
Erinacin B is a active product that can be extracts from the mycelia of Hericium erinaceum. Erinacin B shows potent stimulating activity of nerve growth factor (NGF)-synthesis .
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Cat. No.: HY-P99820
CAS No.: 1632282-27-9
Synonyms: NV-01

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Ranevetmab (NV-01) is a caninised anti-NGF monoclonal antibody (mAb). Ranevetmab can alleviate pain, and is used for the research of degenerative joint disease (DJD) pain .
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Cat. No.: HY-N3938
CAS No.: 110414-77-2
Gelsemiol is the main active ingredient in Verbena littoralis H. B. K.. Gelsemiol enhanced nerve growth factor (NGF) -induced axonal elongation in PC12D cells .
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Cat. No.: HY-P991711
CAS No.: 2975573-74-9
Povovetug is a humanized IgG1κ chimeric monoclonal antibody inhibitor targeting NGF/bNGF. Povovetug has a significant analgesic activity. Povovetug can be used for central neuroinflammation like chronic radicular pain research .
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Cat. No.: HY-N15385
CAS No.: 137592-04-2
Hericenone D, an orally active pancreatic lipase inhibitor, can be found in Hericium erinaceus. Hericenone D reduces lipid absorption and stimulates nerve growth factor NGF gene expression. Hericenone D can be used for the research of menopausal obesity .
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Cat. No.: HY-P3709
CAS No.: 852805-92-6
Target:  

p62 E1/E2/E3 Enzyme

Research Areas:  

Neurological Disease

TRAF6 peptide is a specific TRAF6-p62 inhibitor. TRAF6 peptide potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke .
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Cat. No.: HY-P990474
Synonyms: AS2886401-00

Target:  

Trk Receptor

Research Areas:  

Inflammation/Immunology

Anti-NGF/bNGF Antibody is a CHO-expressed humanized antibody that targets NGF/bNGF. Anti-NGF/bNGF Antibody has a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 144.14 kDa. The isotype control for Anti-NGF/bNGF Antibody can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).
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Cat. No.: HY-165616
CAS No.: 309711-72-6
Target:  

Trk Receptor

Research Areas:  

Neurological Disease

NS 1231 is a neurotrophic-like compound with neuroprotective effect. NS 1231 can rescue nerve growth factor (NGF)-differentiated PC12 cells from death induced by withdrawal of trophic factors. NS 1231 can stimulate NGF-induced neurite outgrowth of undifferentiated PC12 cells. NS 1231 can be used for the research of neurological disease, such as stroke .
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Cat. No.: HY-P99200
CAS No.: 902141-80-4

Target:  

Trk Receptor

Research Areas:  

Neurological Disease

Fulranumab is a human IgG2 monoclonal antibody against nerve growth factor (NGF) and can be used for the research of pain .
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Cat. No.: HY-P991324

Research Areas:  

Inflammation/Immunology

MEDI-7352 is a human bispecific antibody (bsAb) targeting NGF/bNGF & TNF. MEDI-7352 can be used in osteoarthritis (OA) pain research .
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Cat. No.: HY-E70869
Target:  

Trk Receptor

Research Areas:  

Neurological Disease

TRKA (also named NTRK1) is a potential new member of the tyrosine kinase gene family. TRKA is a receptor tyrosine kinase that is phosphorylated in response to NGF. A single transmembrane domain divides TRKA into an extracellular domain, important for NGF binding, and an intracellular tyrosine kinase domain, important for signal transduction. TRKA(NTRK1) Recombinant Human Active Protein Kinase is a recombinant TRKA(NTRK1) protein that can be used to study TRKA(NTRK1)-related functions .
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Cat. No.: HY-N3928
CAS No.: 173294-74-1
Garciniaxanthone E is a xanthone compound. Garciniaxanthone E significantly enhances cellular nerve growth factor (NGF)-mediated neurite outgrowth in PC12D cells. Garciniaxanthone E contributes to basic research and medicinal development in neurodegenerative diseases .
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Cat. No.: HY-P991622
MNAC13 is a kind of mouse IgG1 chimeric antibody, targeting to human TrkA. MNAC13 inhibits the NGF dependent signaling pathway by specifically binding to TrkA receptors. MNAC13 has good analgesic effect and long-lasting efficacy. MNAC13 can be used for researches on inflammatory and chronic pain .
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Cat. No.: HY-P3709A
Target:  

p62 E1/E2/E3 Enzyme

Research Areas:  

Neurological Disease

TRAF6 peptide TFA is a specific TRAF6-p62 inhibitor. TRAF6 peptide TFA potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide TFA has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke .
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