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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
156 Results for "
RNA-binding cleft
" in MedChemExpress (MCE) Product Catalog:
Products (156)
156 Results for "RNA-binding cleft" in MCE Product Catalog:
Cat. No.: HY-113499B
Target:
Research Areas:
cis-Malonylcarnitine lithium is an ester compound and a metabolite of Malonyl CoA (HY-115899). The level of cis-Malonylcarnitine lithium is closely related to some diseases, such as malonic aciduria, non-syndromic cleft lip with or without cleft palate, etc .
Target:
Reference Standards Insecticide Cholinesterase (ChE) Reactive Oxygen Species (ROS) Apoptosis
Research Areas:
Carbaryl (Standard) is the analytical standard of Carbaryl (HY-B1315). This product is intended for research and analytical applications. Carbaryl is the inhibitor for acetylcholinesterase that inhibits the degradation of acetylcholine in the synaptic cleft, leads to the accumulation of acetylcholine and causes neurotoxicity. Carbaryl can be used as an insecticide.
Cat. No.: HY-B1315S1
CAS No.: 362049-56-7
Target:
Isotope-Labeled Compounds Insecticide Cholinesterase (ChE) Reactive Oxygen Species (ROS) Apoptosis
Research Areas:
Carbaryl-d7 is the deuterium labeled Carbaryl (HY-B1315). Carbaryl is the inhibitor for acetylcholinesterase that inhibits the degradation of acetylcholine in the synaptic cleft, leads to the accumulation of acetylcholine and causes neurotoxicity. Carbaryl can be used as an insecticide .
Cat. No.: HY-181846
CAS No.: 1065567-62-5
Target:
Research Areas:
nTRD22 is an RNA-binding allosteric modulator targeting TDP-43. nTRD22 binds to the N-terminal domain of TDP-43, thereby allosterically regulating the RNA-binding domain of TDP-43 and reducing its RNA-binding ability. nTRD22 decreases the TDP-43 protein level in primary motor neurons. nTRD22 alleviates motor dysfunction in amyotrophic lateral sclerosis models. nTRD22 is applicable to related research on amyotrophic lateral sclerosis .
Cat. No.: HY-B0268S1
CAS No.: 2930288-95-0
Cat. No.: HY-W240322
CAS No.: 370582-94-8
PSF-IN-1 (Compound No.10-3) is a RNA-binding protein (PSF) inhibitor and can effectively inhibit the PSF-RNA interaction (IC50: 2.2 pM). PSF-IN-1 can increase histone acetylation, inhibit tumor cell proliferation and induce apoptosis. PSF-IN-1 has antitumor activity .
Cat. No.: HY-158905
CAS No.: 2923694-73-7
Synonyms: MTDB-Alk
Target:
MTDB-Alkyne (MTDB-Alk) is a β-coronavirus pseudoknot RNA-binding ligand that binds to the β-coronavirus pseudoknot RNA structure on the SARS-CoV-2 genome. MTDB-Alkyne can be used to synthesize Proximity-Induced Nucleic Acid Degrader (PINAD) for degrading SARS-CoV-2 RNA. MTDB-Alkyne is applicable to research related to the development of SARS-CoV-2-targeted RNA probes .
Cat. No.: HY-155237
LIN28-IN-1 (compound 5) is an inhibitor of the RNA-binding and regulatory protein LIN28 and binds to the LIN28 cold shock domain (CSD). LIN28-IN-1 effectively inhibits the interaction between LIN28 and let-7 miRNA (IC50: 5.4 μM), blocking the negative impact of LIN28 on epigenetic gene regulation. LIN28-IN-1 significantly inhibits the proliferation of JAR cancer cells expressing LIN28 (IC50: 6.4 μM) .
Cat. No.: HY-P76261
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CIRBP; Glycine-Rich RNA binding Protein; Cold Inducible RNA binding Protein; A18 HnRNP; Cold-Inducible RNA-binding Protein; Cold Inducible RNA-binding Protein; CIRP; Testicular Tissue Protein Li 39; Glycine-Rich RNA-binding Protein CIRP; A18HNRNP
Species:
Human
Source:
E. coli
Cat. No.: HY-B0268S2
Cat. No.: HY-B0268AR
CAS No.: 84294-96-2
Synonyms: Enoxacin sesquihydrate (Standard); AT-2266 hydrate (Standard); CI-919 hydrate (Standard)
Enoxacin (hydrate) (Standard) is the analytical standard of Enoxacin (hydrate). This product is intended for research and analytical applications. Enoxacin hydrate (Enoxacin sesquihydrate), a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase (IC50=126 μg/ml) and topoisomerase IV (IC50=26.5 μg/ml). Enoxacin hydrate is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. Enoxacin hydrate has potent activities against gram-positive and -negative bacteria. Enoxacin hydrate is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing [4].
Cat. No.: HY-P705425
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CIRBP; Glycine-Rich RNA binding Protein; Cold Inducible RNA binding Protein; A18 HnRNP; Cold-Inducible RNA-binding Protein; Cold Inducible RNA-binding Protein; CIRP; Testicular Tissue Protein Li 39; Glycine-Rich RNA-binding Protein CIRP; A18HNRNP
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P811967
Synonyms: RBM12B; RNA binding Motif Protein 12B; RNA-binding Protein 12B; RNA-binding Motif Protein 12B; MGC:33837
Cat. No.: HY-P811967A
Synonyms: RBM12B; RNA binding Motif Protein 12B; RNA-binding Protein 12B; RNA-binding Motif Protein 12B; MGC:33837
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
