239 Results for "

active component

" in MedChemExpress (MCE) Product Catalog:
Products (239)

239 Results for "active component" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-Y0078
CAS No.: 104-54-1
Cinnamyl Alcohol is an active component from chestnut flower, inhibits increased PPARγ expression, exhibits anti-obesity, antioxidant and anti-inflammatory activities .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-N7948
CAS No.: 35997-20-7
Isomaltotetraose is an orally active branched isomaltooligosaccharide with α-(1,6) glycosidic linkages. Isomaltotetraose is a prebiotic oligosaccharide present in honey and also a component of isomaltooligosaccharide mixtures. Isomaltotetraose maintains the growth of Prevotella or sustains the *Prevotella* enterotype in both in vitro systems and mouse models .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-N1374
CAS No.: 31008-18-1
Magnolin, a major component of Magnolia liliiflora, inhibits the Ras/ERKs/RSK2 signaling axis by targeting the active pocket of ERK1 and ERK2 with IC50s of 87 nM and 16.5 nM, respectively.
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-N2237
CAS No.: 94356-26-0
Synonyms: Quzhaqigan
Piceatannol 3'-O-glucoside, an active component of Rhubarb, activates endothelial nitric oxide (NO) synthase through inhibition of arginase activity with IC50s of 11.22 μM and 11.06 μM against arginase I and arginase II, respectively.
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-W269593
CAS No.: 335-76-2
Synonyms: PFDA
Research Areas:  

Metabolic Disease

Perfluorodecanoic acid (PFDA) is an orally active perfluoroalkyl substance. Perfluorodecanoic acid causes dysfunction of rat fetal Leydig cells via endoplasmic reticulum stress-mediated changes in lipid components. Perfluorodecanoic acid reduces testosterone biosynthesis in rat R2C Leydig cells by inducing endoplasmic reticulum stress. Perfluorodecanoic acid can be used in studies related to fetal Leydig cell dysfunction .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-N0367
CAS No.: 4180-23-8
Synonyms: (E)​-Anethole
Trans-Anethole ((E)-Anethole) is an orally active phenylpropene derivative found in Foeniculum vulgare that is estrogenic at low concentrations and cytotoxic at high concentrations in tumor cell lines. Trans-Anethole also has anti-aflatoxin, anti-thrombotic and anti-diabetic activities. Trans-Anethole is an important odor component in plants such as fennel, myrtle, liquorice, and camphor .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-N1987
CAS No.: 50298-90-3
Cucurbitacin IIb is an active component isolated from Hemsleya amabilis, induces apoptosis with anti-inflammatory activity. Cucurbitacin IIb inhibits phosphorylation of STAT3, JNK and Erk1/2, enhances the phosphorylation of IκB and NF-κB (p65), blocks nuclear translocation of NF-κB (p65) and decreases mRNA levels of IκBα and TNF-α .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-W017212
CAS No.: 103-26-4
Synonyms: Methyl 3-phenylpropenoate
Methyl cinnamate (Methyl 3-phenylpropenoate), an active component of Zanthoxylum armatum, is a widely used natural flavor compound. Methyl cinnamate (Methyl 3-phenylpropenoate) possesses antimicrobial activity and is a tyrosinase inhibitor that can prevent food browning. Methyl cinnamate (Methyl 3-phenylpropenoate) has antiadipogenic activity through mechanisms mediated, in part, by the CaMKK2-AMPK signaling pathway .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-N1511
CAS No.: 108340-60-9
Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells . Ganoderic acid D induces HeLa human cervical carcinoma apoptosis .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-N2115
CAS No.: 7518-22-1
Synonyms: Chikusetsusaponin IV
Araloside A (Chikusetsusaponin IV), triterpenoid saponins, is an orally active component of Aralia elata. Araloside A shows low-renin-inhibitory activity with an IC50 of 77.4 μM. Araloside A can inhibit cell proliferation and induce apoptosis. Araloside A suppresses inflammatory cytokines IL-1β and IL-6 production. Araloside A can be used for the researches of cancer, inflammation and cardiovascular disease, such as renal cell carcinoma and rheumatoid arthritis .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-B0837
CAS No.: 155569-91-8
Synonyms: MK-244
Emamectin Benzoate (MK-244) is an orally active nervoussystem toxicant by binding g-aminobutyric (GABA) receptor in insects. Emamectin Benzoate is one of semi-synthetic derivative of Avermectin (HY-15311) with a broadspectrum of insecticidal and acaricidal activity. Emamectin Benzoate induces ROS-mediated DNA damage and cell apoptosis. Emamectin Benzoate, a mixture of the natural Emamectin B1a benzoate and Emamectin B1b benzoate, has the main component of Emamectin B1a benzoate .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-N2118
CAS No.: 521-32-4
Bilobetin, an active component of Ginkgo biloba, can reduce blood lipids and improve the effects of insulin. Bilobetin ameliorated insulin resistance, increased the hepatic uptake and oxidation of lipids, reduced very-low-density lipoprotein triglyceride secretion and blood triglyceride levels, enhanced the expression and activity of enzymes involved in β-oxidation and attenuated the accumulation of triglycerides and their metabolites in tissues. Bilobetin also increased the phosphorylation, nuclear translocation and activity of PPARα accompanied by elevated cAMP level and PKA activity .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-125865
CAS No.: 9000-71-9
Purity:  97.40%
Casein is an orally active phosphoprotein that can be separated into various electrophoretic components, such as α2-Casein, κ-Casein, β-casein, and γ-casein. Casein has also been blended and grafted with other polymers, cross-linkers, or monomers to improve its functional properties. Casein enhances calcium absorption and reduces the extent of fissure as well as smooth-surface caries. Casein promotes proliferation of prostate cancer. Casein has various applications in the paper, leather, textile, and food industries, serving as coatings, adhesives, and packaging materials .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N7819
CAS No.: 1921-70-6
Synonyms: Norphytane
Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil . Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N6948
CAS No.: 115-95-7
Linalyl acetate is the principal components of many plant essential oils. Linalyl acetate exhibits anti-anxiety, anti-inflammatory, anti-diabetic, anti-stress, and cardiovascular-regulatory effects. Linalyl acetate is orally active .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-107553
CAS No.: 1403-36-7
Purity:  95.3%
Target:  

HSP Apoptosis

Research Areas:  

Cancer

Chetomin, an active component of Chaetomium globosum, is a heat shock protein 90/hypoxia-inducible factor 1 alpha (Hsp90/HIF1α) pathway inhibitor. Chetomin is a potent, nontoxic non-small cell lung cancer cancer stem cells (NSCLC CSC)-targeting molecule .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N0511
CAS No.: 475-80-9
Synonyms: Aristolochic acid II
Aristolochic acid B (Aristolochic Acid II) is an orally active major component of aristolochic acid (AA). Aristolochic acid B can be isolated from plants of the genus Aristolochica. Aristolochic acid B forms DNA adducts. Aristolochic acid B is mutagenic. Aristolochic acid B exhibits a greater carcinogenic risk in vivo than Aristolochic acid I (HY-N0510) .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N1972
CAS No.: 37271-16-2
Sennoside C is an orally active component of the traditional Chinese medicine Sennae Folium. Sennoside C can bind to human lysozyme and inhibit its amyloid fibrosis (IC50: 186.20 μM). Sennoside C has certain purgative activity. Sennoside C can be used in the research of diarrhea and anti-amyloid related diseases .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N11019
CAS No.: 291532-17-7
Erinacine P is a cyathane-type diterpenoid antibacterial agent. Erinacine P is isolated from the biosynthesis of mycelia and submerged cultures of Hericium erinaceum. Erinacine P serves as a precursor for the production of important active components such as Erinacine C, A and B. Erinacine P exhibits significant antibacterial activity against Aliivibrio fischeri .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N4290
CAS No.: 25499-90-5
3-Epioleanolic acid is an active component of Verbena officinalis Linn, with anti-inflammatory activity .
loading...
    loading...