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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
75 Results for "
adaptor
" in MedChemExpress (MCE) Product Catalog:
Products (75)
75 Results for "adaptor" in MCE Product Catalog:
Cat. No.: HY-145839
CAS No.: 1815613-44-5
Target:
Research Areas:
AAK1-IN-5 is a highly selective, CNS-penetrable, and orally active adaptor protein-2-associated kinase 1 (AAK1) inhibitor (AAK1 IC50 of 1.2 nM, Filt Ki of 0.05 nM, and cell IC50 of 0.5 nM). AAK1-IN-4 has the potential for the research for neuropathic pain .
Cat. No.: HY-172594
Target:
Research Areas:
HPK1-IN-57 (Compound 10c) is a hematopoietic progenitor kinase 1 (HPK1) inhibitor with an IC50 value of 0.09 nM. HPK1-IN-57 inhibits the activity of HPK1 kinase, hindering the phosphorylation of the downstream adaptor protein SLP76 (IC50 is 33.74 nM) and effectively stimulating the secretion of the T cell activation marker IL-2 (EC50 is 84.24 nM). HPK1-IN-57 is promising for research of tumor immunotherapy .
Cat. No.: HY-119820
CAS No.: 135354-02-8
Synonyms: SR57746A free base
Target:
Akt Dopamine Receptor Trk Receptor 5-HT Receptor PKC JNK ERK
Research Areas:
Xaliproden (SR57746) free base is an orally active, highly selective 5-HT1A receptor agonist. Xaliproden free base activates pertussis toxin-sensitive G protein-coupled signaling cascades, as well as the PKC, ERK1/ERK2, Akt and p21 Ras/MEK-1 pathways. Xaliproden free base also downregulates the JNK/p66/c-Jun signaling pathway, induces phosphorylation of the shc adaptor protein, regulates extracellular dopamine and 5-HT levels, and induces [ 35S]GTPγS labeling in rat brain structures rich in 5-HT1A receptors. Xaliproden free base exerts neurotrophic, neuroprotective, renoprotective, anti-inflammatory, anti-apoptotic, anti-fibrotic and analgesic effects. Xaliproden free base also enhances NGF-induced neurite outgrowth, promotes motor neuron survival, attenuates renal tubular injury and inhibits chemotherapy-induced mechanical allodynia, without activating or altering NGF-induced TrkA receptor activation. Xaliproden free base can be used in the research of motor neuron disease, diabetic nephropathy, chemotherapy-induced peripheral neuropathy, amyotrophic lateral sclerosis, Alzheimer's disease, acute tonic nociceptive pain, inflammatory pain, depression and anxiety .
Cat. No.: HY-P70050
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CRADD; RIP-Associated Protein With A Death Domain; CARD And Death Domain Containing adaptor Protein; Caspase And RIP adaptor With Death Domain; CASP2 And RIPK1 Domain Containing adaptor With Death Domain; Death Domain Containing Protein CRADD; RAIDD; Deat
Species:
Human
Source:
E. coli
Cat. No.: HY-P70304
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: NCK1; Non-Catalytic Region Of Tyrosine Kinase; Prev. NCK; SH2/SH3 adaptor Protein NCK-Alpha; NCKalpha; NCK adaptor Protein 1 Isoform 2; SH2/SH3 Adapter Protein NCK-Alpha; NCK adaptor Protein 1 Isoform 3; SH2/SH3 Adapter Protein NCK1; NCK adaptor Protein 1
Species:
Human
Source:
E. coli
Cat. No.: HY-P703082
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: MAVS; Mitochondrial Antiviral-Signaling Protein; Mitochondrial Antiviral Signaling Protein; CARD Adapter Inducing Interferon Beta; Cardif; Virus-Induced Signaling adaptor; IPS-1; Virus-Induced-Signaling Adapter; VISA; CARD adaptor Inducing IFN-Beta; KIAA1
Species:
Human
Source:
E. coli
Cat. No.: HY-P87158
Synonyms: Adapter-related protein complex 1 subunit gamma-1 antibody; adaptor protein complex AP 1 gamma 1 subunit antibody; adaptor protein complex AP 1 subunit gamma 1 antibody; adaptor protein complex AP-1 subunit gamma-1 antibody; adaptor related protein complex 1 gamma 1 subunit antibody; ADTG antibody; AP 1 complex subunit gamma 1 antibody; AP-1 complex subunit gamma-1 antibody; AP1G1 antibody; AP1G1_HUMAN antibody; Adapter-related protein complex 1 subunit gamma-1 antibody; adaptor protein complex AP 1 gamma 1 subunit antibody; adaptor protein complex AP 1 subunit gamma 1 antibody; adaptor protein complex AP-1 subunit gamma-1 antibody; adaptor related protein complex 1 gamma 1 subunit antibody; ADTG antibody; AP 1 complex subunit gamma 1 antibody; AP-1 complex subunit gamma-1 antibody; AP1G1 antibody; AP1G1_HUMAN antibody; CLAPG1 antibody; Clathrin assembly protein complex 1 gamma 1 large chain antibody; Clathrin assembly protein complex 1 gamma large chain antibody; Clathrin assembly protein complex 1 gamma-1 large chain antibody; Clathrin associated/assembly/adaptor protein large gamma 1 antibody; Gamma1 adaptin antibody; Gamma1-adaptin antibody; Golgi adaptor HA1/AP1 adaptin gamma subunit antibody; Golgi adaptor HA1/AP1 adaptin subunit gamma 1 antibody; Golgi adaptor HA1/AP1 adaptin subunit gamma-1 antibody; MGC18255 antibody;
Cat. No.: HY-P77053
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LAMTOR2; Ragulator Complex Protein LAMTOR2; Prev. ROBLD3; Endosomal adaptor Protein P14; MAPBPIP; MAPBP-Interacting Protein; Ragulator2; MAPKSP1 adaptor Protein; MAPKSP1AP; Mitogen-Activated Protein-Binding Protein-Interacting Protein (MAPBPIP); ENDAP; Mi
Species:
Human
Source:
E. coli
Cat. No.: HY-P71379
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TRAT1; T-Cell Receptor-Associated Transmembrane Adapter 1; Prev. TCRIM; T Cell Receptor Interacting Molecule; TRIM; T-Cell Receptor-Interacting Molecule; HSPC062; T Cell Receptor Associated Transmembrane adaptor 1; Pp29/30
Species:
Human
Source:
E. coli
Cat. No.: HY-P811763
Synonyms: ADTB2, CLAPB1, AP2B1, AP-2 complex subunit beta, AP105B, adaptor protein complex AP-2 subunit beta, adaptor-related protein complex 2 subunit beta, Beta-2-adaptin, Beta-adaptin, Clathrin assembly protein complex 2 beta large chain, Plasma membrane adaptor HA2/AP2 adaptin beta subunit
Cat. No.: HY-P811763A
Synonyms: ADTB2, CLAPB1, AP2B1, AP-2 complex subunit beta, AP105B, adaptor protein complex AP-2 subunit beta, adaptor-related protein complex 2 subunit beta, Beta-2-adaptin, Beta-adaptin, Clathrin assembly protein complex 2 beta large chain, Plasma membrane adaptor HA2/AP2 adaptin beta subunit
Cat. No.: HY-P702056
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MYD88; Mutant Myeloid Differentiation Primary Response 88; MYD88 Innate Immune Signal Transduction adaptor; TLR adaptor MYD88; Myeloid Differentiation Primary Response Protein MyD88; MYD88D; Myeloid Differentiation Primary Response 88; IMD68; Myeloid Diff
Species:
Human
Source:
E. coli
Cat. No.: HY-P702057
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MYD88; Mutant Myeloid Differentiation Primary Response 88; MYD88 Innate Immune Signal Transduction adaptor; TLR adaptor MYD88; Myeloid Differentiation Primary Response Protein MyD88; MYD88D; Myeloid Differentiation Primary Response 88; IMD68; Myeloid Diff
Species:
Human
Source:
E. coli
Cat. No.: HY-P85621
Synonyms: Adapter protein GRID; GADS; GADS protein; GRAP-2; Grap2; GRAP2_HUMAN; GRB-2-like protein; GRB2-related adapter protein 2; GRB2-related adaptor protein 2; GRB2-related protein with insert domain; GRB2L; GRBLG; GRBX; Grf-40; Grf40 adapter protein; Grf40; GRID; Growth factor receptor-binding protein; Growth factor receptor-bound protein 2-related adaptor protein 2; GRPL; Hema; Hematopoietic cell-associated adapter protein GrpL; Hematopoietic cell-associated adaptor protein GRPL; Mona; p38; Protein GADS; SH3-SH2-SH3 adapter Mona; SH3-SH2-SH3 adaptor molecule.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
