15823 Results for "

antibody array

" in MedChemExpress (MCE) Product Catalog:
Products (15823)

15823 Results for "antibody array" in MCE Product Catalog:

30
30 Cited Publications
Cat. No.: HY-19792
CAS No.: 139504-50-0
Synonyms: DM1; Maytansinoid DM1
Research Areas:  

Cancer

Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. Mertansine can be attached to a monoclonal antibody with a linker to create an antibody-drug conjugate (ADC) .
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27
27 Cited Publications
Cat. No.: HY-P99144

Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology

Anti-Mouse PD-1 Antibody (RMP1-14) is an anti-mouse PD-1 IgG2a antibody. Anti-Mouse PD-1 Antibody (RMP1-14) can be used for the study of colon carcinoma .
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26
26 Cited Publications
Cat. No.: HY-17422
CAS No.: 59277-89-3
Synonyms: Aciclovir; Acycloguanosine
Research Areas:  

Infection Cancer

Acyclovir (Aciclovir) is a potent, orally active antiviral agent. Acyclovir has antiherpetic activity with IC50 values of 0.85 μM and 0.86 μM for HSV-1 and HSV-2, respectively. Acyclovir induces cell cycle perturbation and apoptosis. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia .
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26
26 Cited Publications
Cat. No.: HY-17422A
CAS No.: 69657-51-8
Synonyms: Aciclovir sodium; Acycloguanosine sodium
Research Areas:  

Infection Cancer

Acyclovir (Aciclovir) sodium is a potent, orally active antiviral agent. Acyclovir sodium has antiherpetic activity with IC50 values of 0.85 μM and 0.86 μM for HSV-1 and HSV-2, respectively. Acyclovir sodium induces cell cycle perturbation and apoptosis. Acyclovir sodium prevents bacterial infections during induction therapy for acute leukaemia .
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24
24 Cited Publications
Cat. No.: HY-P9903
CAS No.: 946414-94-4
Synonyms: BMS-936558; ONO-4538; MDX-1106

Target:  

PD-1/PD-L1

Research Areas:  

Infection Cancer

Nivolumab is a programmed death receptor-1 (PD-1) blocking human IgG4 antibody to treat advanced (metastatic) non-small cell lung cancer.
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24
24 Cited Publications
Cat. No.: HY-P80450
Synonyms: Phospholipid hydroperoxide glutathione peroxidase GPX4, PHGPx, Glutathione peroxidase 4, GPx-4, GSHPx-4, Gpx4

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

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22
22 Cited Publications
Cat. No.: HY-P99001

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology Cancer

Human IgG1 kappa, Isotype Control is a human monoclonal antibody that is the isotype control of human IgG1 kappa antibody .
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22
22 Cited Publications
Cat. No.: HY-D0825
CAS No.: 943298-08-6
Synonyms: Sulfo-Cyanine7
Target:  

Fluorescent Dye

Research Areas:  

Others

CY7 is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
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20
20 Cited Publications
Cat. No.: HY-P9908
CAS No.: 331731-18-1
Synonyms: Anti-Human TNF-alpha, Human antibody; ABBV-3373 antibody

Target:  

TNF Receptor Bacterial

Research Areas:  

Inflammation/Immunology Cancer

Adalimumab is a human monoclonal IgG1 antibody targeting tumour necrosis factor α (TNF-α).
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20
20 Cited Publications
Cat. No.: HY-P99145

Target:  

PD-1/PD-L1

Research Areas:  

Cancer

Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) is an anti-mouse PD-L1/B7-H1 IgG2b antibody inhibitor derived from host rat. Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) blocks PD-1 signaling. Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) can be used for the research of cancer, such as colon cancer .
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16
16 Cited Publications
Cat. No.: HY-P9913A
CAS No.: 174722-31-7
Rituximab (anti-CD20) is an anti-CD20 chimeric monoclonal antibody used to treat certain autoimmune diseases and types of cancer .
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16
16 Cited Publications
Cat. No.: HY-P9913
CAS No.: 174722-31-7
Synonyms: Anti-Human CD20 type I, Chimeric antibody; HSDB 7455; IDEC-C2B8
Rituximab is an anti-CD20 chimeric monoclonal antibody used for research of certain autoimmune diseases and cancer.
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16
16 Cited Publications
Cat. No.: HY-108847
CAS No.: 185243-69-0
Purity:  99.20%

Target:  

TNF Receptor Bacterial

Research Areas:  

Inflammation/Immunology Cancer

Etanercept, a dimeric fusion protein that binds TNF, acts as a TNF inhibitor. Etanercept competitively inhibits the binding of both TNF-α and TNF-β to cell surface TNF receptors, rendering TNF biologically inactive. Etanercept shows efficacy against rheumatoid arthritis, juvenile idiopathic arthritis, and plaque psoriasis .
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14
14 Cited Publications
Cat. No.: HY-P99003

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Human IgG4 (S228P) kappa, Isotype Control, a human-derived monoclonal antibody, is an isotype control for human IgG4κ antibody.
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14
14 Cited Publications
Cat. No.: HY-B0199
CAS No.: 128794-94-5
Synonyms: RS 61443; TM-MMF
Mycophenolate mofetil (RS 61443) is the morpholinoethylester proagent of Mycophenolic acid. Mycophenolate mofetil inhibits de novo purine synthesis via the inhibition of inosine monophosphate dehydrogenase (IMPDH). Mycophenolate mofetil shows selective lymphocyte antiproliferative effects involve both T and B cells, preventing antibody formation .
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14
14 Cited Publications
Cat. No.: HY-B0199A
CAS No.: 116680-01-4
Synonyms: RS 61443 hydrochloride; TM-MMF hydrochloride
Mycophenolate mofetil (RS 61443; TM-MMF) hydrochloride is an orally active antimetabolic immunosuppressant with antiproliferative and anti-inflammatory properties. Mycophenolate mofetil hydrochloride significantly inhibits the production of B, T lymphocytes and the proliferation of smooth muscle cells by selectively blocking the de novo purine synthesis pathway. Mycophenolate mofetil hydrochloride effectively reduces adventitial inflammation, medial necrosis and intimal thickening in rat aortic allografts, and decreases the number of lymphocytes expressing the IL-2 receptor, thereby delaying xenograft rejection. Mycophenolate mofetil hydrochloride shows certain toxicity in a hamster-to-rat limb xenotransplantation model when used in combination with FK506 (HY-13756). Mycophenolate mofetil hydrochloride is widely used in studies related to allograft arteriosclerosis (chronic rejection) .
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13
13 Cited Publications
Cat. No.: HY-P9927A
CAS No.: 1229022-83-6

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Secukinumab (Anti-Human IL-17A) is a fully human anti-interleukin-17A monoclonal antibody. Anti-Human IL-17A can be used for research in psoriasis pathogenesis .
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13
13 Cited Publications
Cat. No.: HY-P9927
CAS No.: 1229022-83-6
Synonyms: AIN457

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Secukinumab (AIN457) is a high affinity, human monoclonal antibody targeted against interleukin (IL)-17A. Secukinumab is the first-in-class anti-IL-17 agent used for the research of plaque psoriasis, ankylosing spondylitis and psoriatic arthritis .
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13
13 Cited Publications
Cat. No.: HY-101070
CAS No.: 1228105-51-8
Purity:  99.23%
Synonyms: DM1-SMCC
Research Areas:  

Cancer

SMCC-DM1 (DM1-SMCC) is a agent-linker conjugate composed of a potent microtubule-disrupting agent DM1 and a linker SMCC to make antibody agent conjugate (ADC) .
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13
13 Cited Publications
Cat. No.: HY-K0218A

MCE Streptavidin Agarose 6FF, a 6% highly cross-linked agarose reagent coupled with recombinant streptavidin, is an affinity chromatography medium for separation and purification of biotinylated peptides, antibodies, lectins, etc. The total binding capacity of Streptavidin Agarose 6FF is more than 200 nmol of D-Biotin/mL settled resin.

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