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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
37 Results for "
fission
" in MedChemExpress (MCE) Product Catalog:
Products (37)
37 Results for "fission" in MCE Product Catalog:
Target:
Research Areas:
THP104c is a mitochondrial fission inhibitor .
Cat. No.: HY-N11128
CAS No.: 19941-91-4
Target:
Cat. No.: HY-15511R
CAS No.: 10537-47-0
Synonyms: Tyrphostin 9 (Standard); Malonoben (Standard)
Target:
Tyrphostin A9 (Standard) is the analytical standard of Tyrphostin A9. This product is intended for research and analytical applications. Tyrphostin A9, a PDGFR inhibitor, is a potent inducer of mitochondrial fission. Tyrphostin A9 emerged as the most potent and selective of 51 tyrosine kinase inhibitors tested against the TNF-induced respiratory burst. Tyrphostin A9 has anti-influenza virus activities.
Cat. No.: HY-N0703R
CAS No.: 51938-32-0
Cat. No.: HY-P10650
CAS No.: 1588388-60-6
Cat. No.: HY-175221
WHN-11 is an amino-Artemisinin (HY-B0094) derivative with anti-cancer activity against various cancer cell lines. WHN-11 deprives the cell of ATP, activates autophagy, and causes subsequent cell death by apoptosis. WHN-11 alters cellular protein homeostasis pathways to induce mitochondrial fission and dysfunction. WHN-11's anti-cancer activity is independent of substantive ROS production. WHN-11 can be used for the study of triple-negative breast cancer (TNBC) .
Cat. No.: HY-P70941
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FIS1; Mitochondrial fission Molecule; Prev. TTC11; FIS1 Homolog; H_NH0132A01.6; HFis1; CGI-135; fission 1 (Mitochondrial Outer Membrane) Homolog (S. Cerevisiae); Tetratricopeptide Repeat Protein 11; fission 1 (Mitochondrial Outer Membrane) Homolog (Yeast)
Species:
Human
Source:
E. coli
Cat. No.: HY-P702782
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MTFP1; HSPC242; Mitochondrial fission Process 1; Mitochondrial fission Protein MTP18; MTP18; Mitochondrial Protein 18 KDa; Mitochondrial fission Process Protein 1; Alternative Protein MTFP1; Mitochondrial 18 KDa Protein
Species:
Human
Source:
E. coli
Cat. No.: HY-E71549
Target:
Research Areas:
2-Hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase (EC 1.3.1.40): broad specificity; reduces a number of compounds produced by Pseudomonas from aromatic hydrocarbons by ring fission.
Cat. No.: HY-E71444
Target:
Research Areas:
2,6-Dioxo-6-phenylhexa-3-enoate hydrolase (EC 3.7.1.8) cleaves the products from biphenol, 3-isopropylcatechol and 3-methylcatechol produced by EC 1.13.11.39 biphenyl-2,3-diol 1,2-dioxygenase, by ring-fission at a -CO-C bond.
Cat. No.: HY-103661R
CAS No.: 791835-21-7
Research Areas:
BI-6C9 (Standard) is the analytical standard of BI-6C9 (HY-103661). This product is intended for research and analytical applications. BI-6C9 is a highly specific BH3 interacting domain (Bid) inhibitor, which prevents mitochondrial outer membrane potential (MOMP) and mitochondrial fission, and protects the cells from mitochondrial apoptosis inducing factor (AIF) release and caspase-independent cell death in neurons .
Cat. No.: HY-134878
CAS No.: 2227449-25-2
Research Areas:
Amyloid-β-Drp1 PPI-IN-1 is an Amyloid-β-Drp1 protein-protein interaction inhibitor. Amyloid-β-Drp1 PPI-IN-1 inhibits Aβ-Drp1 interaction and decreases Drp1 and Aβ levels. Amyloid-β-Drp1 PPI-IN-1 inhibits excessive mitochondrial fission and promotes mitochondrial fusion and biogenesis. Amyloid-β-Drp1 PPI-IN-1 also alleviates oxidative stress and improves mitochondrial function, and can be used for Alzheimer's disease research .
Cat. No.: HY-19938
CAS No.: 1030303-53-7
Target:
Research Areas:
MTL-005 is a boron-containing radiosensitizer used in Boron Neutron Capture Therapy (BNCT). MTL-005 enriches the boron-10 isotope in tumor tissues, causing nuclear fission under thermal neutron irradiation, releasing high linear energy transfer (LET) α particles and lithium ions, which selectively destroy tumor cells while minimizing damage to surrounding normal tissues. MTL-005 significantly controlls the tumor progression in the SCCVII squamous cell carcinoma mouse model and prolonged the survival of the mice. MTL-005 can be used to study solid tumors such as head and neck cancer.
Cat. No.: HY-D3148
CAS No.: 1804107-88-7
Target:
Research Areas:
TPE-Ph-In is a mitochondria-targeted voltage-sensitive probe that can be used for mitochondrial membrane potential detection, mitochondrial imaging of animal and plant cells and tissues, mouse sperm activity indication, and detection of mitochondrial membrane potential changes associated with early apoptosis. TPE-Ph-In is non-fluorescent in solution, but emits strong fluorescence when aggregated via restriction of intramolecular rotation/movement, and its fluorescence intensity is directly correlated with local probe concentration or mitochondrial membrane potential level. TPE-Ph-In can penetrate cell membranes, target mitochondria through charge-dependent accumulation, has low cytotoxicity and high photostability, and enables super-resolution imaging of plant mitochondrial fission, fusion and cristae structures. The excitation wavelengths of TPE-Ph-In include 450 nm, 488 nm, and 489 nm, while its emission wavelengths include 551-661 nm, 660 nm, and 694 nm. TPE-Ph-In can be used for studies on mitochondrial dysfunction associated with early apoptosis .
Cat. No.: HY-N19735
CAS No.: 144678-18-2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
