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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
165 Results for "
programmed cell death
" in MedChemExpress (MCE) Product Catalog:
Products (165)
165 Results for "programmed cell death" in MCE Product Catalog:
Target:
Cathepsin B, Bovine spleen is a cysteine protease and is involved in multiple kinds of programmed cell death (including apoptosis, pyroptosis, ferroptosis, necroptosis, and autophagic cell death) .
Cat. No.: HY-P99618
CAS No.: 2377419-89-9
Synonyms: IBI-315; BH2950
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Cat. No.: HY-P99480
CAS No.: 1918149-01-5
Synonyms: M7824; MSB0011359C
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Cat. No.: HY-P99203
CAS No.: 1801342-60-8
Synonyms: REGN-2810; SAR-439684
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Cat. No.: HY-P99473
CAS No.: 1987854-08-9
Synonyms: BI-505
Cat. No.: HY-P99114
CAS No.: 2256084-03-2
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Cat. No.: HY-P10439
CAS No.: 2349354-64-7
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Cat. No.: HY-P99941
CAS No.: 2079108-44-2
Synonyms: INCMGA-00012; MGA-012
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Cat. No.: HY-101058A
Purity: 95.11%
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PD1-PDL1-IN 1 TFA (compound 16) is a potent programmed cell death 1 (PD-1) inhibitor. PD1-PDL1-IN 1 TFA is useful as immune modulator .
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PD-1-IN-17 is a programmed cell death-1 (PD-1) inhibitor extracted from patent WO2015033301A1, Compound 12, inhibits 92% splenocyte proliferation at 100 nM .
Cat. No.: HY-P99938
CAS No.: 2403647-03-8
Synonyms: HX008
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S6K1-IN-DG2 (Compound 66) is a p70S6K inhibitor (IC50: < 100 nM) .
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PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor with an IC50 of 92.3 nM .
Cat. No.: HY-P10950
CAS No.: 1931111-41-9
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RIPK3-IN-3 (compound 20) is a selective inhibitor of RIP kinase RIPK3 (IC50=10 nM). RIPK3 mediates the phosphorylation of Mixed Lineage Kinase (MLKL) and causes necroptosis, while RIPK3-IN-3 inhibits p-MLKL oligomerization and thereby inhibits necroptosis. RIPK3-IN-3 also downregulates CXCL5 secretion and inhibits AsPC-1 cell migration and invasion .
Cat. No.: HY-P10370
CAS No.: 721397-24-6
Cat. No.: HY-P991122
CAS No.: 3037124-22-1
Synonyms: ONO-4685
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Propiolamide is a monooxygenase (MMO) system activator and glutathione peroxidase 4 (GPX4) inhibitor. Propiolamide induces ROS production through interaction with the MMO system. Propiolamide promotes the accumulation of intracellular cytotoxic lipid peroxides and induces ferroptosis. Propiolamide induces programmed cell death via the apoptosis pathway. Propiolamide can be used in cancer research .
Cat. No.: HY-101058
CAS No.: 2005454-12-4
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PD1-PDL1-IN 1 (compound 16) is a potent programmed cell death 1 (PD-1) inhibitor. PD1-PDL1-IN 1 is useful as immune modulator .
Cat. No.: HY-151066
CAS No.: 2447065-99-6
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BMS-1233 is an orally active inhibitor for programmed cell death-ligand 1 (PD-L1), with IC50 of 14.5 nM. BMS-1233 promotes cell death of HepG2 in a Jurkat T cell and HepG2 cell co-culture model, exhibits antitumor activity against melanoma in mouse model .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
