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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
199 Results for "
tissue factor
" in MedChemExpress (MCE) Product Catalog:
Products (199)
199 Results for "tissue factor" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-P4744A
1
1 Cited Publications
Cat. No.: HY-16382
CAS No.: 871266-63-6
Target:
Research Areas:
PCI-27483 is a FVIIa/tissue factor inhibitor, with antitumour effects.
1
1 Cited Publications
Cat. No.: HY-P99271
CAS No.: 1418628-81-5
Synonyms: Anti-Human F3 Recombinant Antibody
Target:
Research Areas:
1
1 Cited Publications
Synonyms: Penequinine hydrochloride
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
Penehyclidine (Penequinine) hydrochloride, a anticholinergic agent, is a selective antagonist of M1 and M3 receptors. Penehyclidine hydrochloride activates NF-kβ in lung tissue and inhibits the release of inflammatory factors. Penehyclidine hydrochloride can alleviate the pulmonary inflammatory response in rats with chronic obstructive pulmonary disease (COPD) undergoing mechanical ventilation .
1
Research Areas:
ARC19499 sodium is an aptamer that inhibits tissue factor pathway inhibitor (TFPI) , thereby enabling clot initiation and propagation via the extrinsic pathway. The core aptamer binds tightly and specifically to TFPI. ARC19499 sodium blocks TFPI inhibition of both factor Xa and the TF/factor VIIa complex. ARC19499 sodium corrects thrombin generation in hemophilia A and B plasma and restores clotting in FVIII-neutralized whole blood.
1
1 Cited Publications
Cat. No.: HY-P71358A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TFPI2; Placental Protein 5; tissue factor Pathway Inhibitor 2; Retinal Pigment Epithelium Cell factor 1; TFPI-2; tissue factor Pathway Inhibitor; PP5; TFPI2 Variant; REF1
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P74527A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TFPI2; Placental Protein 5; tissue factor Pathway Inhibitor 2; Retinal Pigment Epithelium Cell factor 1; TFPI-2; tissue factor Pathway Inhibitor; PP5; TFPI2 Variant; REF1
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P77227
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TFPI; EPI; Prev. LACI; tissue factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor); Extrinsic Pathway Inhibitor; Lipoprotein-Associated Coagulation Inhibitor; TFPI1; Anti-Convertin; tissue factor Pathway Inhibitor; TFI
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-W016393
CAS No.: 2305-13-7
Target:
1
1 Cited Publications
Cat. No.: HY-P73372
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SERPINF1; Testis tissue Sperm-Binding Protein Li 70n; Prev. PEDF; Serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived factor), Member 1; EPC-1; Proliferation-Inducing Protein 35; Pigment Epithelium-Derived factor; Serpin F
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P70498A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SERPINF1; Testis tissue Sperm-Binding Protein Li 70n; Prev. PEDF; Serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived factor), Member 1; EPC-1; Proliferation-Inducing Protein 35; Pigment Epithelium-Derived factor; Serpin F
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P70106
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCN2; CCN Family Member 2; Prev. CTGF; IBP-8; IGFBP8; SEMDLSL; Connective tissue Growth factor; IGFBP-8; Hypertrophic Chondrocyte-Specific Protein 24; NOV2; Insulin-Like Growth factor-Binding Protein 8; KMD; IGF-Binding Protein 8; Cellular Communication N
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P70602
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CCN2; CCN Family Member 2; Prev. CTGF; IBP-8; IGFBP8; SEMDLSL; Connective tissue Growth factor; IGFBP-8; Hypertrophic Chondrocyte-Specific Protein 24; NOV2; Insulin-Like Growth factor-Binding Protein 8; KMD; IGF-Binding Protein 8; Cellular Communication N
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P78104
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CCN2; CCN Family Member 2; Prev. CTGF; IBP-8; IGFBP8; SEMDLSL; Connective tissue Growth factor; IGFBP-8; Hypertrophic Chondrocyte-Specific Protein 24; NOV2; Insulin-Like Growth factor-Binding Protein 8; KMD; IGF-Binding Protein 8; Cellular Communication N
Species:
Human
Source:
HEK293
1
Target:
Research Areas:
MTI-31 (LXI-15029) is a potent, orally active and highly selective inhibitor of mTORC1 and mTORC2. MTI-31 is selective for mTOR (Kd: 0.20 nM) versus PIK3CA, PIK3CB and PIK3G with >5,000 fold selectivity in mTOR binding assays. MTI-31 shows an IC50 of 39 nM for mTOR in LANCE assay of mTOR substrate phosphorylation with 100 μM ATP. MTI-31 can be used for the research of breast cancer .
1
1 Cited Publications
(E/Z)-Necrosulfonamide is a racemic compound of Necrosulfonamide (HY-100573). Necrosulfonamide is a MLKL and Gasdermin D (GSDMD) inhibitor, capable of separately inhibiting necroptosis and pyroptosis of cells. Necrosulfonamide does not affect the activation of upstream signals, but specifically inhibits the downstream executor oligomerization step. Necrosulfonamide reduces the expression of the key kinases NLRP3 and caspase-1 involved in necroptosis and pyroptosis, activate the Nrf2 pathway and the downstream antioxidant enzymes, and also downregulates a variety of inflammatory factors. Necrosulfonamide plays significant roles in various diseases such as neurodegenerative diseases (such as Parkinson’s disease), tissue damage and ischemia-reperfusion injury, inflammatory bowel disease, osteoarthritis and fracture repair, and hair loss by regulating two important programmed necrosis pathways.
1
1
1 Cited Publications
Cat. No.: HY-D1423
CAS No.: 68654-25-1
Target:
Research Areas:
Dibromobimane is a Fluorescent dye and probe that can be used for the detection of intracellular reduced glutathione and the analysis of spatial proximity of closely adjacent cysteine thiol groups. Dibromobimane activates fluorescence through binding to thiol groups; its excitation/emission wavelengths are Ex/Em = 393/477 nm for glutathione detection, and Ex/Em = 385/477 nm for cysteine thiol cross-linking. Dibromobimane uses two equivalent bromomethyl groups to cross-link cysteine thiolates with a distance ranging from 3-6 Å. Dibromobimane can be applied to 96-well microplate-based high-throughput assays for labeling intracellular glutathione, and its fluorescence signal is normalized against nuclear staining results to eliminate the impact of cell density .
1
1 Cited Publications
Cat. No.: HY-P7422
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TXN; TRDX; TRX; TRX1; Thioredoxin; Trx; ATL-derived factor; ADF; Surface-associated sulphydryl protein; SASP; TXN Delta 3; Thioredoxin-2; Allergen Hom S Trx; Thioredoxin Delta 3; Thioredoxin, Mitochondrial; Testicular tissue Protein Li 199; ADF; Surface-A
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P73432
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TXN; TRDX; TRX; TRX1; Thioredoxin; Trx; ATL-derived factor; ADF; Surface-associated sulphydryl protein; SASP; TXN Delta 3; Thioredoxin-2; Allergen Hom S Trx; Thioredoxin Delta 3; Thioredoxin, Mitochondrial; Testicular tissue Protein Li 199; ADF; Surface-A
Species:
Mouse
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
