48 Results for "

postmenopausal

" in MedChemExpress (MCE) Product Catalog:
Products (48)

48 Results for "postmenopausal" in MCE Product Catalog:

Cat. No.: HY-P0284A
Target:  

MMP

Research Areas:  

Metabolic Disease

C-telopeptide TFA is a cross-linked peptide of type I collagen that is released during bone resorption and correlates with bone mineral density (BMD). C-telopeptide TFA can be used in studies related to postmenopausal osteoporosis .
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Cat. No.: HY-B0631S
CAS No.: 1035437-39-8
Alendronic acid-d6 is the deuterium labeled Alendronic acid. Alendronic acid, a bisphosphonate, is a farnesyl diphosphate synthase (FDPS) inhibitor. Alendronic acid inhibits osteoclast-mediated bone resorption. Alendronic acid shows efficacy in postmenopausal osteoporosis, malignant hypercalcemia and Paget’s disease .
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Cat. No.: HY-N0943
CAS No.: 24808-04-6
(−)-Epiafzelechin is a COX-1 inhibitor with an IC50 of approximately 15 μM against COX-1 activity. (−)-Epiafzelechin also exhibits DPPH free radical scavenging activity, with an EC50 of 20.9 μM. (−)-Epiafzelechin promotes osteoblast differentiation by increasing ALP activity, ECM collagen content and Runx2 expression, while reducing the growth of osteoclast precursors and RANKL-induced TRAP activity, thereby regulating the bone remodeling process. (−)-Epiafzelechin alleviates ovariectomy-induced bone loss. (−)-Epiafzelechin can be used in studies related to bone remodeling, postmenopausal osteoporosis, inflammatory responses and oxidative stress .
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Cat. No.: HY-14752
CAS No.: 753449-67-1
Synonyms: SB 751689
Target:  

CaSR

Research Areas:  

Metabolic Disease Endocrinology

Ronacaleret (SB 751689) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates endogenous parathyroid hormone release from the parathyroid glands. Ronacaleret (SB 751689) is used for the study of postmenopausal osteoporosis .
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Cat. No.: HY-15104
CAS No.: 702686-96-2
Synonyms: SB 751689A
Target:  

CaSR

Research Areas:  

Metabolic Disease Endocrinology

Ronacaleret hydrochloride (SB 751689A) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates endogenous parathyroid hormone release from the parathyroid glands. Ronacaleret hydrochloride (SB 751689A) is used for the study of postmenopausal osteoporosis .
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Cat. No.: HY-N0976
CAS No.: 210537-04-5
Synonyms: 11b-Hydroxy-11b,1-dihydromedicarpin
1,11b-Dihydro-11b-hydroxymedicarpin (11b-Hydroxy-11b,1-dihydromedicarpin) is a pterocarpan from Ononis viscosa subsp. breviflora is a Medicarpin derivative . Medicarpin, a natural pterocarpan, heals cortical bone defect by activation of Notch and Wnt canonical signaling pathways . Medicarpin prevents arthritis in post-menopausal conditions by arresting the expansion of TH17 cells and pro-inflammatory cytokines. Medicarpin down-regulates pro-inflammatory cytokines like TNF-α, IL-6 and IL-17A, while up-regulates anti-inflammatory cytokine IL-10 in arthritis (CIA) model of mice .
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Cat. No.: HY-P1463
CAS No.: 57014-02-5
Synonyms: Thyrocalcitonin eel
Research Areas:  

Endocrinology

Calcitonin, eel is the thyroid hormone peptide that contributes to the regulation of calcium homeostasis, widely used in the research of postmenopausal osteoporosis.
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Cat. No.: HY-P1463A
Synonyms: Thyrocalcitonin eel TFA
Research Areas:  

Others

Calcitonin, eel TFA is the thyroid hormone peptide that contributes to the regulation of calcium homeostasis, widely used in the research of postmenopausal osteoporosis .
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Cat. No.: HY-122359B
CAS No.: 199583-01-2
Synonyms: L-Centchroman fumarate; L-Ormeloxifene fumarate
Target:  

Estrogen Receptor/ERR

Research Areas:  

Others

Levormeloxifene (fumarate) is a stable salt form of Levormeloxifene. Levormeloxifene (fumarate) is an estrogen receptor modulator that plays an important role in prevention of postmenopausal bone loss .
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Cat. No.: HY-159741
CAS No.: 105051-87-4
Synonyms: FCE 24928
Target:  

Cytochrome P450

Research Areas:  

Cancer

Minamestane (FCE 24928) is a selective and competitive aromatase inhibitor with an IC50 value of 45.7 nM. Minamestane is promising for research of postmenopausal breast cancer .
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Cat. No.: HY-122359
CAS No.: 78994-23-7
Synonyms: L-Centchroman; L-Ormeloxifene
Target:  

Estrogen Receptor/ERR

Research Areas:  

Endocrinology Cancer

Levormeloxifene (L-Centchroman) is a selective estrogen receptor modulator (SERM), which prevents and ameliorates postmenopausal osteoporosis. Levormeloxifene causes multiple adverse gynecological effects .
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Cat. No.: HY-123047S
Tibolone-d5 is deuterium labeled Tibolone. Tibolone is a broad spectrum gonadal steroid agonist with progestagenic, androgenic, and estrogenic activities. Tibolone can be used for postmenopausal osteoporosis research .
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Cat. No.: HY-123047R
CAS No.: 5630-53-5
Tibolone (Standard) is the analytical standard of Tibolone. This product is intended for research and analytical applications. Tibolone is a broad spectrum gonadal steroid agonist with progestagenic, androgenic, and estrogenic activities. Tibolone can be used for postmenopausal osteoporosis research .
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Cat. No.: HY-W698952S
Research Areas:  

Endocrinology

3β hydroxy Tibolone-d5 is deuterium labeled Tibolone. Tibolone is a broad spectrum gonadal steroid agonist with progestagenic, androgenic, and estrogenic activities. Tibolone can be used for postmenopausal osteoporosis research .
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Cat. No.: HY-P991362

Target:  

TNF Receptor

Research Areas:  

Cancer

GB-223 is a human monoclonal antibody (mAb) targeting TNFSF11/RANKL/CD254. GB-223 can be used in Giant cell tumour of bone and Postmenopausal osteoporosis research .
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Cat. No.: HY-108685S
CAS No.: 1309283-09-7
Synonyms: Alendronic acid-d4 monosodium salt
Alendronate-d4 (sodium) (Alendronic acid-d4 (monosodium salt)) is deuterium labeled Alendronate sodium. Alendronate sodium is an orally active nitrogen-containing bisphosphonate. Alendronate sodium potently inhibits bone resorption. Alendronate sodium is used for the research of postmenopausal osteoporosis .
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Cat. No.: HY-111309
CAS No.: 847235-85-2
Target:  

Androgen Receptor

Research Areas:  

Endocrinology

LGD-2941 is an orally active, potent and selective androgen receptor modulator. LGD-2941 shows excellent anabolic activity in muscle with reduced effect on the prostate in a rat model of hypogonadism. LGD-2941 also improves bone strength in a rat model of post-menopausal osteoporosis .
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Cat. No.: HY-135593
CAS No.: 183060-99-3
Target:  

Others

Research Areas:  

Endocrinology

LY88074 analog 1 is a benzothiophene compound with nitrogen-containing non-basic side chains, Compound 26, extracted from patent EP0747380A1. LY88074 analog 1 is an agent for alleviating the symptoms of post-menopausal symptoms, such as osteoporosis, cardiovascular related pathological conditions, and estrogen-dependent cancer. LY88074 analog 1 can be used alone or in combination with estrogen or progestin .
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Cat. No.: HY-178478
CAS No.: 86009-41-8
Research Areas:  

Metabolic Disease

PDE1-IN-11 (Compound 5cc) is an orally active and highly selective PDE1A1 inhibitor. PDE1-IN-11 increases intracellular cAMP and cGMP levels, activating the PKA-CREB and NO-cGMP-PKG signaling pathways, promoting osteoblast differentiation and bone formation, while suppressing osteoclastogenesis and bone resorption. PDE1-IN-11 is promising for research of postmenopausal osteoporosis (PMO) and other bone metabolism disorders .
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Cat. No.: HY-N20183
Category:  

Extract

Target:  

Others

Pyrola herb extract is an extract of Pyrola (a type of herb) that can be used in research on postmenopausal osteoporosis.
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